Protein Alignment EcR and nhr-176

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_507045.2
• Gene: nhr-176 / 184496
• WormBaseID: WBGene00008830
• Length: 345
• Species: Caenorhabditis elegans
• Alignment Length: 349
• Identity: 81/349 - (23%)
• Similarity: 122/349 - (34%)
• Gaps: 108/349 - (30%)

  Fly   249 KKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVT---KSAVYC---CKFGRACE 307
            |||...|        |||||..::...:.|.:|..|..||||.|.   |....|   |.|.:.
 Worm     3 KKSTIQP--------CLVCGQSSNSILFGAPSCRACGEFFRRKVISNFKIKNNCLGECSFAKK-- 57

  Fly   308 MDMYMRRKCQECRLKKCLAVGMRPECVVPENQC-AMKRREKKAQKEKDKMTTSPSSQHGGNGSL- 370
                ..:.||.||.:|||..||..:.|...... ::...||...:|.::..:  ..:||.|.:.
 Worm    58 ----SMKPCQSCRFQKCLEAGMLEKMVFSRKAIYSISNFEKSILEELEEAYS--KLEHGRNETFN 116

  Fly   371 -ASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGY 434
             .|.....|...|.|: .||.    ..|.::.|.:::..||:. |.                 |.
 Worm   117 PKSDSNPKFCSHEELN-NTCT----IDIQIILDNLISYFQAKK-PM-----------------GK 158

  Fly   435 EQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKAC 499
            ||..                             :|.:..||.|.....||..|.:...|
 Worm   159 EQDD-----------------------------VLKMHFIVPFVLFDTAFRAIGKSSYI------ 188

  Fly   500 SSEVMML---RMARRYDHSSDSIFFANN--------RSYTRDSYKMAGMADNIEDLLHFCRQMFS 553
            |.:..|.   .:.:.|..||:|....||        .||.:.|||:            ...:|..
 Worm   189 SPDGTMFGGSYVEKLYQDSSNSKIGVNNGKTSREIMESYWKVSYKI------------LKSEMEL 241

  Fly   554 MKVDNVEYALLTAIVIFSDRPGLE 577
            :::|..|:.||:|::.:..  |||
 Worm   242 LQLDRSEFLLLSALIYWDF--GLE 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	29/96 (30%)
		NR_LBD_EcR	420..652	CDD:132736	33/169 (20%)
nhr-176	NP_507045.2	ZnF_C4	9..75	CDD:197701	25/79 (32%)
		HOLI	167..309	CDD:214658	29/117 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165585
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840