Protein Alignment EcR and nhr-170

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_507673.2
• Gene: nhr-170 / 183795
• WormBaseID: WBGene00008309
• Length: 420
• Species: Caenorhabditis elegans
• Alignment Length: 482
• Identity: 102/482 - (21%)
• Similarity: 162/482 - (33%)
• Gaps: 141/482 - (29%)

  Fly   232 SPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSA 296
            |.||.:..::.|                    |.:|...:.|.|:...||..|..||||:|..:.
 Worm     5 SSSSEMTYFTVN--------------------CEICQKTSHGLHFGLETCRACAAFFRRTVVLNR 49

  Fly   297 VYCC--KFGRACEMDMYMRRK-CQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTT 358
            .|.|  |.|: ||:......| |:.||.|||:.:||..|.|         |.:.|...| |..:.
 Worm    50 KYKCIQKTGK-CEIGAGGEEKLCKFCRFKKCIDLGMTTENV---------RTDFKDDSE-DTSSQ 103

  Fly   359 SPSSQHGGNGSLASGGGQDFVKK--EILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTY--- 418
            ||.|    ..|:.....|..|.|  ..::.....|...|...|:....:.| ::|.|....|
 Worm   104 SPQS----TSSMEVTSSQQIVAKVRNRVEYYIVNPKTQAPAMLIDVNAIIK-ESRAILETHYFPD 163

  Fly   419 -NQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITIL---TVQL--IVEF 477
             :.:|.:..|        |.....|.:|.    |.:|.:...|.|:....:.   .||:  ...:
 Worm   164 EDLIAHLNPL--------QRMSHSLHKIR----EKQSWSPEFFEHVKFYKMFQWWEVQMRDTATW 216

  Fly   478 AKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADNIE 542
            ......|.::|..::|.:.|                     |.:|..|.:.|  |.|:.
 Worm   217 LMHSDEFRRLPSHEKIAIFK---------------------IVWAVWRRFER--YTMSA------ 252

  Fly   543 DLLHFCRQMFSMKVDNVEYALLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMS 607
                   |||..|             .:.::..:...|......:|:||...:   :.|..:..:
 Worm   253 -------QMFGQK-------------CYDEKIHVHNHQFAARFGNYHIDYSNV---SDHGFERFN 294

  Fly   608 LVFYAKLLS----ILTELRTLGNQNAEMCFSL-----KLKNRKL--------PKFLEEIWDVHAI 655
            .||..|::.    |:.....|.....|:.:.|     ....|:|        .:|||||
 Worm   295 NVFGGKMIRYFDIIVKPYLELNLSETEVTYILCQIVWNYAGRRLQGQTQAAGERFLEEI------ 353

  Fly   656 PPSVQSHLQITQEENERLERAERMRAS 682
                .::|....||..|.|...:..||
 Worm   354 ----SNNLHSYYEEAARKEENPKNYAS 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	31/92 (34%)
		NR_LBD_EcR	420..652	CDD:132736	44/253 (17%)
nhr-170	NP_507673.2	ZnF_C4	16..87	CDD:197701	28/91 (31%)
		Hormone_recep	187..397	CDD:278530	45/252 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165507
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840