Protein Alignment EcR and nhr-158

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_504068.1
• Gene: nhr-158 / 182731
• WormBaseID: WBGene00015901
• Length: 359
• Species: Caenorhabditis elegans
• Alignment Length: 471
• Identity: 104/471 - (22%)
• Similarity: 161/471 - (34%)
• Gaps: 144/471 - (30%)

  Fly   210 LGMQHTPRSDSVNSISSGRDDLSPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGY 274
            :.:.|||               ||||:.   |:..|.|..:.|           |::|...|...
 Worm     1 MSVYHTP---------------SPSSAT---SSPLSIDIPQRK-----------CVICLRPAYSN 36

  Fly   275 HYNALTCEGCKGFFRRSVTKSAVYCCKF-GRACEMDMYMRRKCQECRLKKCLAVGM--RPECVVP 336
            :|..|||:.||.||||.|.....|.||: ||...:......||:.||.::||..||  :|..:..
 Worm    37 NYGVLTCDACKMFFRRIVILKKDYKCKYDGRCAHVAKSPMVKCKGCRYQQCLDAGMSFQPTFLEL 101

  Fly   337 ENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLP 401
            .|             |||                             ||:
 Worm   102 TN-------------EKD-----------------------------LDI--------------- 109

  Fly   402 DEILAKCQARNIPSLTYNQLAV-------IYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVS 459
                         |:|...|..       |.|..:..|........|.||:     :.:|:|...
 Worm   110 -------------SVTIGNLVFLDTRKSRIMKTQFTDDNLSLEQIVDTRRM-----KMKSRTINK 156

  Fly   460 FRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMA-RRYDHSSDSIFFAN 523
            :....:.|.|.:...|:....|....|:...|::.||:..:|:..:|..| |.|....|.:...:
 Worm   157 YISPQDWTFLALYTTVDLLLNLDFMEKLSTPDKLILLRHSASKCALLGGAMRTYLDKKDRMTTVD 221

  Fly   524 NRS-YTRDSYKMAGMADNIEDLLHFCRQMFSMK-----VDNVEYALLTAIV-----IFSDRPGLE 577
            .:. |.::...:.|.....:..|...|.:...|     |...|..|::||:     :|.|:....
 Worm   222 GQDIYPKEMRALLGFQQGADQFLDRVRSLLISKLAELDVTTEECILISAIIFCDPAVFYDQDNPN 286

  Fly   578 KAQLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLG---NQNAE------MCF 633
            ..|:|.|.|..:...|..|.|         |:::....|.||.|.:|.   .:|.|      |.|
 Worm   287 AQQIVSAQQQNFTSALSQYCL---------LMYHRNGPSRLTNLLSLCPIIQKNFEDLQYLTMVF 342

  Fly   634 SLKLKNRKLPKFLEEI 649
            .|.:|..|..|..:|:
 Worm   343 RLAVKGMKFKKIEQEL 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	29/92 (32%)
		NR_LBD_EcR	420..652	CDD:132736	57/258 (22%)
nhr-158	NP_504068.1	ZnF_C4	25..92	CDD:197701	26/77 (34%)
		HOLI	164..330	CDD:214658	39/174 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165515
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840