Protein Alignment EcR and nhr-65

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_001024219.1
• Gene: nhr-65 / 180230
• WormBaseID: WBGene00003655
• Length: 401
• Species: Caenorhabditis elegans
• Alignment Length: 500
• Identity: 97/500 - (19%)
• Similarity: 157/500 - (31%)
• Gaps: 202/500 - (40%)

  Fly   262 ELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLA 326
            |.|.||||..:|.|:.|.||..|..||||:.::      ||.|.||..:....||:.|||::|..
 Worm    11 ERCKVCGDTGNGMHFGAFTCRACAAFFRRAASR------KFLRKCENHLIFALKCKNCRLQRCYE 69

  Fly   327 VGMR-----------------PECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGG 374
            .||.                 |:..||      |..|:...:....:...|...
 Worm    70 AGMSSENFQFCRDLIGAKGAIPKLKVP------KSFEQTVGRPYFVLQCDPEVL----------- 117

  Fly   375 GQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQP-- 437
               |:::.|:|   |.|            :|.|.:                |||.:  |.|.|
 Worm   118 ---FLRRNIID---CVP------------LLEKAE----------------KLIEF--GSESPVF 146

  Fly   438 SEEDLRRIMS--QPDENESQTDVSF------RHITEITILTVQLIVEFAKGLPAFTKIPQEDQIT 494
            |:..|.::..  |..::.....|.|      :.|............::...|..|..:.:..|:|
 Worm   147 SKNRLLKLAQGLQQFQDAKSNQVKFVQKMGQKEIMSFFETDFLCATKWFTYLDEFQFLDKNQQLT 211

  Fly   495 LLKA----------------------CSSEVMMLRMARRY----------DHSSDSIFFANNRSY 527
            |::.                      |....:|:.....:          |.|..:.|......|
 Worm   212 LMQGIWHVWSRLHKLAVSAMGRRRGICDKNTVMVSHQNEFAVCDLNEIEVDMSWCTNFSNEQMRY 276

  Fly   528 ----TRDSY------KMAGMADN-IE-------------------DLLHFCRQMFSMKVDNVEYA 562
                :.|||      :|.|:..| :|                   ::|.||.:|.....|:
 Worm   277 FLDTSHDSYVYQVMDEMLGLKPNDVELSYMMCQLCLQYAGQRFQGEILEFCEKMLGFLADD---- 337

  Fly   563 LLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLRI--YILNRHCGDSMSLVFYAKLLSILTELRTLG 625
                                  :.|||:..||:  |...           .|||:.|...::
 Worm   338 ----------------------LHSYYVKQLRMPNYAAR-----------LAKLMKINNRIK--- 366

  Fly   626 NQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEEN 670
               .:|   ||::.|:....:.:||.:..      ||.:..|:.|
 Worm   367 ---VDM---LKMRQRQEISRVFDIWTIDF------SHPEFIQDAN 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	34/105 (32%)
		NR_LBD_EcR	420..652	CDD:132736	51/305 (17%)
nhr-65	NP_001024219.1	NR_DBD_like	13..75	CDD:295381	28/67 (42%)
		Hormone_recep	165..375	CDD:278530	39/255 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165634
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840