Protein Alignment EcR and nhr-70

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_507636.1
• Gene: nhr-70 / 180217
• WormBaseID: WBGene00003660
• Length: 389
• Species: Caenorhabditis elegans
• Alignment Length: 412
• Identity: 98/412 - (23%)
• Similarity: 162/412 - (39%)
• Gaps: 103/412 - (25%)

  Fly   256 APRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECR 320
            |.|.::..|.:||:..:|.|:.|..|..|..||||||..:.:|.|:....|::...:|..|:.||
 Worm     3 AGRGEKPPCSICGEVGNGVHFGAEACRACAAFFRRSVALNKLYRCRGDGNCDILSTIRCMCRACR 67

  Fly   321 LKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQ-----HGGNGSLASGGGQDFVK 380
            ..||:||||:.|.|       .|.|:...::..|  ..||.|.     :.|:|....||   |..
 Worm    68 FAKCMAVGMKREAV-------QKYRDAYGKRGSD--VESPGSSSVSLPNQGDGFGPPGG---FNP 120

  Fly   381 KEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRI 445
            ....|.:     :...:|:|           .:.|..|.:|..:.:::.:..|
 Worm   121 NSTFDSV-----EECGMPIL-----------TMLSQNYEKLQSVRRVVHHDQG------------ 157

  Fly   446 MSQPDENESQTDVSFRHITEITILTVQLIVEF-AKGLPAFTKIPQEDQITLLK------------ 497
             |...:..:...||::....::.....|:.:: ....|.|..:.::.:|.|.:
 Worm   158 -SSVFQMRTPKAVSYKEANIVSSKECDLVADWILNSYPGFADLHKDQKIILFRNFFLPFVILQGG 221

  Fly   498 --AC---SSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQMFSM--- 554
              ||   .|:|::|......|.|....|:     |..|..::.    :.||.:......||:
 Worm   222 HFACIHNRSDVIILASGDYIDCSHPETFY-----YDPDGRQLM----SSEDAVRMFASSFSIYRR 277

  Fly   555 ---------KVDNVEYALLTAIVIFSDRPGLE---------KAQLVEAIQSYYIDTLRIYILNRH 601
                     .||:.|:..|.::|:|.  .|||         ..::.||||.   :.|..|...||
 Worm   278 NVTDPMLRDNVDSFEFFALCSLVLFD--TGLEGQSEECIRVSRRIREAIQR---EILYHYRNVRH 337

  Fly   602 CGD-SMSLVFYAKLLSILTELR 622
            ..| ||.|   |.|||:|..|:
 Worm   338 IEDPSMRL---ANLLSLLPALQ 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	31/89 (35%)
		NR_LBD_EcR	420..652	CDD:132736	51/243 (21%)
nhr-70	NP_507636.1	ZnF_C4	10..79	CDD:197701	27/68 (40%)
		Hormone_recep	162..365	CDD:278530	48/212 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165576
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840