Protein Alignment EcR and nhr-193

DIOPT Version :10

• Sequence 1: NP_724460.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_507131.1
• Gene: nhr-193 / 180098
• WormBaseID: WBGene00010215
• Length: 384
• Species: Caenorhabditis elegans
• Alignment Length: 350
• Identity: 72/350 - (20%)
• Similarity: 121/350 - (34%)
• Gaps: 99/350 - (28%)

  Fly   264 CLVCGDR-ASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGR-ACEMDMYMRRKCQECRLKKCLA 326
            ||:||.: ..|.|:....|..|..||||...      .|:.| .|..:....|.|:.||||:|.|
 Worm     4 CLICGAKNTRGNHFGVRCCRACAVFFRRRAG------TKYLRLKCSSENCGNRFCKPCRLKRCFA 62

  Fly   327 VGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEP 391
            .||                            |....||          .:|.:|..|:..:   |
 Worm    63 AGM----------------------------TIEHFQH----------NRDLIKSTIVPKI---P 86

  Fly   392 PQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLI------WYQDGYEQP--SEEDLRRIMSQ 448
            ...|.:...|..::. |    :|..:|.:..|...::      .::.|.|.|  ....|:::.:.
 Worm    87 RSFANVVGRPSFVIF-C----VPQESYRKTFVDLNVLIEKAGEIFEKGPENPYIGSTQLKKLAAA 146

  Fly   449 PDENESQTDVSFRHIT--EITILTVQLIVEFAKGL---PAFTKIPQEDQITL------------- 495
            .:........||..::  |::.......:..||.|   ..|.|||::..|.|
 Worm   147 SNFTMDWNRRSFEPLSHGEMSYFWEFYFLRTAKWLTYFEEFKKIPRDLMIKLLLSFWHVFSRLDK 211

  Fly   496 ---------LKACSSEVMMLRMARRYDHSSDSIFFANNRSY-TRDSY----KMAGMADNIEDLLH 546
                     ||.||.:...:......|.....:.|....:| .:|.:    .||.:     ||..
 Worm   212 LITTARARKLKVCSQQTWAMSNGFILDFDKTKVDFWKLSNYPAKDLFYFLNSMAAL-----DLQP 271

  Fly   547 FCRQMFSMKVDNVEYALLTAIVIFS 571
            ..:::..::|.:||:..:.|.:.||
 Worm   272 QVQELQELEVSDVEFNFMLAQLTFS 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_724460.1	NR_DBD_EcR	261..351	CDD:143535	25/88 (28%)
		NR_LBD_EcR	420..652	CDD:132736	34/191 (18%)
nhr-193	NP_507131.1	ZnF_C4	3..68	CDD:197701	26/97 (27%)
		Hormone_recep	158..352	CDD:459675	28/143 (20%)