Protein Alignment EcR and nhr-68

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_001366648.1
• Gene: nhr-68 / 179589
• WormBaseID: WBGene00003658
• Length: 385
• Species: Caenorhabditis elegans
• Alignment Length: 391
• Identity: 92/391 - (23%)
• Similarity: 152/391 - (38%)
• Gaps: 86/391 - (21%)

  Fly   261 EELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCL 325
            :|:||||.|.:|||||...:|.|||.||||:|.|...:.|:|.:.|.:|..:|..|:.||.:|||
 Worm     4 KEVCLVCQDFSSGYHYGIPSCNGCKTFFRRTVMKKQKFVCQFDQNCPVDKSIRCACRFCRFEKCL 68

  Fly   326 AVGM-RPECVVPENQCAMKRREKKAQKE-------KDKMTTSPSSQHGGNGSLASGGG------- 375
            .||| :.......:.....:|.||..:.       .:..:.:|..|.....|..:...
 Worm    69 KVGMDKTSLQASRDPIGYTKRNKKTLRHPMNELSGDESNSCTPDRQLSPLRSFENSLNFLAVRER 133

  Fly   376 -------QDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDG 433
                   ..::.|..|....|..      ||:.|.|.....|...|..|:.:|..|
 Worm   134 SANELRMSSYLPKRSLKQALCSK------PLINDPIFMSKHATVSPRHTFEKLRFI--------- 183

  Fly   434 YEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKA 498
                                :|.|..:.|..:..:||     |:||....|..:|..|:..|:
 Worm   184 --------------------TQDDYHYWHERDWFVLT-----EYAKTFKVFKNMPYHDKTELV-- 221

  Fly   499 CSSEVMMLRMARRY---DHSSDSIFFANNRSY--TRDSYKMAGMADNIEDLLHFCRQMF-SMKVD 557
            |.:.:::..:.:.|   |:..|::.|.:...|  |.:..:.||:......:|....:.| .|:::
 Worm   222 CHAAIVIPVLNQVYNSPDYGLDTVVFPDGTYYDRTHEPTRPAGLNRKKYQVLDLVLKPFREMEIN 286

  Fly   558 NVEYALLTAIVIFSDRPGL----------EKAQLVEAIQSYYI--DTLR--IYILNR--HCGDSM 606
            ..|:|...||...:....:          |:..:.:.:.:|.:  |.|.  ||...|  ..|.||
 Worm   287 FNEFAAFKAITFLNPDADISLESKHAINEERVLITKQLYAYMVQKDGLEKAIYRFGRLILMGTSM 351

  Fly   607 S 607
            |
 Worm   352 S 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	38/90 (42%)
		NR_LBD_EcR	420..652	CDD:132736	41/210 (20%)
nhr-68	NP_001366648.1	NR_DBD_HNF4A	7..82	CDD:143518	34/74 (46%)
		HOLI	193..354	CDD:214658	36/167 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165539
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840