Protein Alignment EcR and nhr-59

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_503624.2
• Gene: nhr-59 / 178707
• WormBaseID: WBGene00003649
• Length: 416
• Species: Caenorhabditis elegans
• Alignment Length: 424
• Identity: 88/424 - (20%)
• Similarity: 143/424 - (33%)
• Gaps: 160/424 - (37%)

  Fly   259 VQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVY--CCKFGRA-CEMDMYMRRKCQECR 320
            |.:..|.|||..:.|.|:.|:||..|..|||| |...|.:  .||.||. |::....|..|::||
 Worm    15 VNQTFCQVCGQESHGAHFGAITCRACAAFFRR-VAAGANFEVKCKDGRGRCKILTNGRSCCKKCR 78

  Fly   321 LKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILD 385
            ||||..:||..:               ..|..:|...||.......:..|   |..:|
 Worm    79 LKKCKDIGMDIQ---------------NFQFNRDSFATSTKVAPSLSTFL---GRPEF------- 118

  Fly   386 LMTCEP------PQHATIPLLPDEILAKCQA-----RNIP-------------SLTYNQLAVIYK 426
            |::|.|      .|:..|.|.|  .:..|:.     |.||             ||.:...|
 Worm   119 LLSCSPGTSASTSQNKFIDLSP--FIKNCKQVLMDDRKIPLAPGKTRLQKLSSSLDFEISA---- 177

  Fly   427 LIWYQDGYEQPSEEDLRRIMS-------QPDENE----------------SQTDVSFRHI----- 463
                   ..:..:.|||::.:       |..|||                ...|..|:.:
 Worm   178 -------NNKKKKTDLRKVSTLGFSEAIQIFENELLMTSKWLAHFEEFHDLGNDFKFKFLECTWN 235

  Fly   464 ----TEITILTVQLI----VEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIF 520
                .|....|..|:    :...||          ::|.|.:.|..::..::.         .:.
 Worm   236 IWNRLERVARTAALLRDQKISNGKG----------NEIILARNCVIDLRTVKF---------EVE 281

  Fly   521 FANNRSYTRDSYKMAGMAD-----NIEDLLHF-----------------C--RQMFSMKVDNVEY 561
            :..|.|.:..||.:.|:.|     .::.::.|                 |  :||.|...:.::
 Worm   282 WFTNYSLSEISYFIEGVGDWSMNKPLQAIIDFNPTEIELNFMLAQISLTCASKQMDSQYQETID- 345

  Fly   562 ALLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLRI 595
                         .|:|. :.:.:.||||..:|:
 Worm   346 -------------NLQKL-IADDLHSYYIKEMRL 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	31/92 (34%)
		NR_LBD_EcR	420..652	CDD:132736	36/236 (15%)
nhr-59	NP_503624.2	ZnF_C4	20..>71	CDD:197701	21/51 (41%)
		Hormone_recep	182..392	CDD:278530	35/218 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165491
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840