Protein Alignment EcR and nhr-18

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_503608.2
• Gene: nhr-18 / 178702
• WormBaseID: WBGene00003617
• Length: 394
• Species: Caenorhabditis elegans
• Alignment Length: 449
• Identity: 97/449 - (21%)
• Similarity: 173/449 - (38%)
• Gaps: 109/449 - (24%)

  Fly   255 PAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVT-KSAVYCCKFGRACEMDMYMRRKCQE 318
            |||......|.||||:.||.|:..::|..|..||||:.| ......|..| .|...:..:..|::
 Worm     2 PAPLFLSGSCEVCGDKTSGRHFGVMSCRACAAFFRRAATWNLEKRICPNG-TCHTSVNGKFNCKQ 65

  Fly   319 CRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASG-GGQDFVKKE 382
            |||||||.|||               ..::.|.::|.::.|..||     |||:. |..:|:
 Worm    66 CRLKKCLDVGM---------------DTRRFQTDRDLISCSAISQ-----SLATFLGRPEFI--- 107

  Fly   383 ILDLMTCEPPQHATIPLLPD---------EILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPS 438
                :.|||.:.:.:....|         ::|.|.....:||.:..|||.              :
 Worm   108 ----LCCEPDRASVLKTTIDVTRLVNIARDMLQKPTNHVLPSNSLEQLAT--------------T 154

  Fly   439 EEDLRRIMSQPDENESQTDVSF--RHITEITILTVQ----LIVEFAKGLPAFTKIPQEDQITLLK 497
            .:::|.:       ||..:|.|  ::....|:.:.:    .:||:......|.::.:..::.::|
 Worm   155 LDNMRCV-------ESNKEVKFIEKYGKVETLKSWEQGFLRVVEWFSNFSEFRELNERLKLEIVK 212

  Fly   498 ACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAG----MADNIEDLLHFCRQMFSMKVD- 557
            :|...      ..|.|..|::   ||     :...||.|    |..|     ..|..|.:.::|
 Worm   213 SCWFS------WTRLDKLSET---AN-----KQINKMLGKSQLMVGN-----GACMNMNNFEIDL 258

  Fly   558 --NVEYALLTAIVIFSDRPGLEKAQLVEAIQ--------SYYIDTLRIYILNRHCGDSMSLVFYA 612
              ...|:|......|....|  |....::||        |..:..:.:::...|.|..:    :.
 Worm   259 SWCTNYSLEQLKYFFQTPNG--KKNFQQSIQDMIDLNPSSIEVSYMLLHLSLEHAGKRL----HG 317

  Fly   613 KLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEENE 671
            ..|.....|..:...|....:..||   ||..:...:..:..|..::::.::|..|:.:
 Worm   318 DALDATENLVQVQANNLHKYYVEKL---KLANYSSRLTQLMRITRTLEADIRIRIEKKQ 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	29/90 (32%)
		NR_LBD_EcR	420..652	CDD:132736	44/252 (17%)
nhr-18	NP_503608.2	NR_DBD_like	11..86	CDD:295381	30/90 (33%)
		Hormone_recep	163..371	CDD:278530	41/235 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165626
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840