Protein Alignment EcR and nhr-103

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_503607.1
• Gene: nhr-103 / 178701
• WormBaseID: WBGene00003693
• Length: 394
• Species: Caenorhabditis elegans
• Alignment Length: 443
• Identity: 109/443 - (24%)
• Similarity: 172/443 - (38%)
• Gaps: 125/443 - (28%)

  Fly   255 PAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVT--KSAVYCCKFGRACEMDMYMRRKCQ 317
            |||......|.:||.:.||.|:..|:|..|..|||||.|  :..|.|.|  ..|::....:..|:
 Worm     2 PAPLFLSGPCEICGQKTSGRHFGVLSCRSCAAFFRRSATWSRKKVQCVK--GTCKIFEDGKFNCK 64

  Fly   318 ECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASG-GGQDFVKK 381
            :||||||:.|||               ..||.|..:|.:::....|     ||.:. |..:|:
 Worm    65 QCRLKKCVEVGM---------------DSKKFQTNRDLISSCSVPQ-----SLCNFLGRPEFI-- 107

  Fly   382 EILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSE--EDLR- 443
                 :.|||.:.:......|.......|:|:......|..:       .:..||.|.  |::|
 Worm   108 -----LCCEPDKASVFKTTIDVTYLVDMAKNLLEKDPCQCPL-------SNSLEQLSTTLENMRG 160

  Fly   444 -------RIMSQPDENES--QTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKAC 499
                   :|:.:..:|||  ..:..|..           .||:......|.::.:..::.:||.|
 Worm   161 MKLNKETQIIKKLGKNESLKTWEQGFLR-----------AVEWFSNFSEFRELDENLKMEILKTC 214

  Fly   500 SSEVMMLRMARRYDHSSDSIFFANNR-SYTRD-SYKMAGMADNIEDLLHFCRQMFSMKVD---NV 559
              .|..:|:    |..|::   ||.| :.|.| |..|.|...        |..|...:||   ..
 Worm   215 --WVSWIRL----DKLSET---ANKRVNATLDNSLLMVGNDS--------CMHMNDYEVDLSWCT 262

  Fly   560 EYALLTAIVIFSDRPGLEK--AQLVEAI-----QSYYIDTLRIYILNRHCGDSM---------SL 608
            .|: |..:..|...|..||  .||::.:     .|..|..:.:.:...|.|..:         ||
 Worm   263 NYS-LEQLAFFFLTPDDEKNYRQLIQDMVDLNPSSTEISYMLLQLSLEHAGKRLQGDILEATESL 326

  Fly   609 V---------FYAKLLSI------LTEL----RTLGNQNAEMCFSLKLKNRKL 642
            |         :|||.|.:      ||:|    |||   .|:|  .|:::.:|:
 Worm   327 VQAQANQLHDYYAKKLKLSNYSSRLTQLMKITRTL---EADM--RLRIEKKKV 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	31/91 (34%)
		NR_LBD_EcR	420..652	CDD:132736	62/275 (23%)
nhr-103	NP_503607.1	ZnF_C4	10..77	CDD:197701	29/83 (35%)
		Hormone_recep	164..371	CDD:278530	55/240 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165625
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840