Protein Alignment EcR and nhr-58

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_503236.1
• Gene: nhr-58 / 178573
• WormBaseID: WBGene00003648
• Length: 393
• Species: Caenorhabditis elegans
• Alignment Length: 434
• Identity: 87/434 - (20%)
• Similarity: 154/434 - (35%)
• Gaps: 122/434 - (28%)

  Fly   262 ELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLA 326
            |.|.:|..::.|.|:...:|..|..||||......|......:.|..:.::   |:.|||.:|.|
 Worm     6 EFCKICDRKSQGIHFGVPSCRACAAFFRRRAGSDLVEKSCMNKKCGKEFFL---CKPCRLVRCYA 67

  Fly   327 VGMRPECVVPENQCAMKRREKKAQKEKDK------MTTSPSSQHGGNGSLASGGGQDFVKKEILD 385
            |||               .|||.|.::|.      :.|.|.|..      ...|...||.
 Worm    68 VGM---------------DEKKFQFDRDALASTVLLNTIPKSFD------KFVGRPQFVH----- 106

  Fly   386 LMTCEPPQHATIPLLPDEILAKCQARNI----PSLT-YNQLAVIYKLIWYQDGY-EQPSEEDLRR 444
              .|:|...:|...:...:|.: :..||    ||.| :.....::||..:.:.: :.|.......
 Worm   107 --FCDPSAPSTSKFIDVRLLVE-KGENILKSGPSWTPHMNKGPLFKLANFHNVFTKMPVNMATNN 168

  Fly   445 IMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLL------------K 497
            :.|:.|.::..   .:..:|..|.||         ....|.|:....::.:|            .
 Worm   169 VFSRGDCSDCW---EYYFLTTATWLT---------NFDEFQKLEHPVKMKILFAIWHMWGRMDKL 221

  Fly   498 ACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQMFSMKVDNVEYA 562
            ||::      :|||....|.....|.:.          |:..:::.|......:...|::.||:
 Worm   222 ACTA------LARRRQQLSAKSEIAQSN----------GLFLDVDTLALDVSWISEFKLEEVEF- 269

  Fly   563 LLTAIVIFSDRPGLEKAQLVEAIQ------------SYYIDTLRIYIL-NRHCGDSMSLV-FYAK 613
                   |.|  |.....|:|.:|            :|.:..:..|.. ||..|:.:.:: .:.:
 Worm   270 -------FID--GFRNWDLMELVQVFVELDPTPIELNYMLAQMSFYYAGNRFQGEILEIMDRFQQ 325

  Fly   614 LLS------ILTELRTLGNQNAEMCFSLKLKN-------RKLPK 644
            :||      .:.|..| .|.:..:...||:.|       ::.||
 Worm   326 ILSDDLHKYYVNERHT-SNYSGRLSRLLKINNAVQSSVRKRRPK 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	25/88 (28%)
		NR_LBD_EcR	420..652	CDD:132736	45/265 (17%)
nhr-58	NP_503236.1	ZnF_C4	8..73	CDD:197701	21/82 (26%)
		Hormone_recep	174..368	CDD:278530	39/232 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165637
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840