Protein Alignment EcR and nhr-99

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_503214.1
• Gene: nhr-99 / 178569
• WormBaseID: WBGene00003689
• Length: 418
• Species: Caenorhabditis elegans
• Alignment Length: 413
• Identity: 82/413 - (19%)
• Similarity: 143/413 - (34%)
• Gaps: 96/413 - (23%)

  Fly   232 SPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSA 296
            ||.|||:      |.|:..     .|......|.:|...:.|.|:.|:||..|..||||......
 Worm     5 SPDSSLS------SLDSPL-----VPTRSMRTCEICDKPSHGKHFGAVTCRACAMFFRRFGRCKN 58

  Fly   297 VYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPS 361
            :..|:....|:........|::|||:||..|||..:..    |..:.:..|...:.|...|.
 Worm    59 MKPCEMNNNCQFPKNGYFNCKKCRLQKCWDVGMTTDTF----QSVISKLAKPTLQVKIPETI--- 116

  Fly   362 SQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAK--------CQARNI----- 413
                  |:|..          :.:|:....|:...    |..|...        .|...|
 Worm   117 ------GTLIG----------LPNLIIFNAPEFEA----PSSICKNFIDVRYLVSQGEQILRTGL 161

  Fly   414 --PSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVE 476
              |.:..|.|..:...:.|......|...::|||        .|.:| |....:..:.|.:.:..
 Worm   162 ETPIIAQNSLEKMALGLEYIRKMRNPKINNIRRI--------GQKEV-FTLWQDDFLKTAKWLTY 217

  Fly   477 FAKGLPAFTKIPQEDQITLLK----------------------ACSSEVMMLRMARR---YDHSS 516
            |::    |.::|...|:..||                      ||||.::::::...   :|...
 Worm   218 FSE----FQQLPDGLQMKFLKSIWKLWSRFERLVTTMIGRRNSACSSNMVLIKLDDTQVVFDIKK 278

  Fly   517 DSIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQMFSMKVDNVEYALLTAIV----IFSDRPGLE 577
            ..:..:....|..:..|:.|.:...|......::|..:...|||.:.:...:    |.....| :
 Worm   279 IDVDVSWQSRYNVEQLKLFGYSYLDEKYDEIIQEMIDLDPTNVELSFMVCQLCLHHIGKKFQG-D 342

  Fly   578 KAQLVEAIQSYYIDTLRIYILNR 600
            ..::.|.:||...:.|..|.:|:
 Worm   343 ILKVAERLQSSIANNLHDYYVNK 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	25/89 (28%)
		NR_LBD_EcR	420..652	CDD:132736	37/210 (18%)
nhr-99	NP_503214.1	ZnF_C4	25..94	CDD:197701	23/68 (34%)
		Hormone_recep	185..395	CDD:278530	35/195 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165485
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840