Protein Alignment EcR and nhr-100

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_501731.1
• Gene: nhr-100 / 177806
• WormBaseID: WBGene00003690
• Length: 437
• Species: Caenorhabditis elegans
• Alignment Length: 446
• Identity: 106/446 - (23%)
• Similarity: 176/446 - (39%)
• Gaps: 93/446 - (20%)

  Fly   253 KGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQ 317
            :.|:| |.:..||||||.....||.|::|.|||||||||:.:...|.|.|...|.::...|.:|:
 Worm    14 RNPSP-VSDTSCLVCGDPHGKRHYGAMSCNGCKGFFRRSIWEKRTYKCSFNNECIIEFKYRNRCR 77

  Fly   318 ECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKE 382
            .||||:||.|||....|..|       |.:|.:.|.|           |:..|.       :|:|
 Worm    78 ACRLKRCLHVGMDANAVRSE-------RTRKIKTEID-----------GDVKLE-------IKEE 117

  Fly   383 ILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQP--------SE 439
            ..|  :.:......:.:.||..:|......|..:.|.:..|:        .:|:|        .:
 Worm   118 PAD--SEDADDECPLDIKPDIAMAWQTKEIIAHMLYEEDRVL--------NWEEPYNKLRYYTMD 172

  Fly   440 EDLRRIMSQPDENESQTDVSF----RHITEITIL------TVQLIVEFAKGLPAFTKIPQEDQIT 494
            .::.:.:..|.:..::|.:::    |.:..|..|      |..|.:::.:.||.:..:..:|:..
 Worm   173 SEVLQAIKDPSQVCARTKINWNSHSRPLITIEALRFNWCRTFTLTIDWFETLPEYRALIDDDKEL 237

  Fly   495 LLKACSSEVMMLRMA-RRYDHSSDSIFFANNRSYTRDS----------------YKMAGMADNIE 542
            |:|.....|..|..| :.|::..|.|.|.:...:.||.                ...:.|||.:
 Worm   238 LVKFSLMPVGWLWYAYKSYEYRCDGIVFVDGSWFPRDKTIQQQVCPTCVLYYGRITESFMADVV- 301

  Fly   543 DLLHFCRQMFSMKVDNVEYALLTAIVIFSDRPGLEKA--QLVEAIQSYYIDTLRIYILNRHCGDS 605
                  ..|..:::|..|..||.||........|.:.  .::...:..|...|..||..:..|..
 Worm   302 ------NSMKELEMDETEMVLLKAICHLQPDYRLTRRGNDVISTGREKYKRALCEYIRMKSNGFM 360

  Fly   606 MSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRK-------LPKFLEEIWDVHA 654
            .:.....||:.||..:..||....|....:.|...:       ||      :|:||
 Worm   361 DASFRLCKLMQILPVVDILGKYEDESALLVSLGETEFNGSGGGLP------YDIHA 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	38/89 (43%)
		NR_LBD_EcR	420..652	CDD:132736	50/275 (18%)
nhr-100	NP_501731.1	NR_DBD_HNF4A	24..98	CDD:143518	36/80 (45%)
		HOLI	210..376	CDD:214658	36/172 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BAC4
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810