Protein Alignment EcR and nhr-105

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_001021303.1
• Gene: nhr-105 / 177476
• WormBaseID: WBGene00003695
• Length: 429
• Species: Caenorhabditis elegans
• Alignment Length: 477
• Identity: 99/477 - (20%)
• Similarity: 178/477 - (37%)
• Gaps: 131/477 - (27%)

  Fly   229 DDLSPSSSLNGYSANESCDAKKSKKGPAPRVQEE-----LCLVCGDRA-SGYHYNALTCEGCKGF 287
            |.:.||..:..:...|       :.||:..::.|     .|||||..| :|:||....|.|||.|
 Worm     5 DPMDPSIPIFQHHEEE-------EAGPSTTIKAEEEDGPCCLVCGRVANTGHHYGVTACLGCKTF 62

  Fly   288 FRRSVTKSAVYCCKFGRAC--EMDMYMRRKCQECRLKKCLAVGMRPECVVPENQC--AMKRREKK 348
            |||.|.:.....||:...|  |..:..:|.|:.||.:|||.|||..:.:.|   |  .:.||.:.
 Worm    63 FRRVVLQKNSPKCKYKNHCRLEKSVNAKRLCRSCRYQKCLEVGMTEDALHP---CRDVIGRRVRN 124

  Fly   349 AQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNI 413
            ...:...:::.||                                   || .|   |:.|:..|:
 Worm   125 NSSDSSPISSPPS-----------------------------------IP-TP---LSICKLMNL 150

  Fly   414 PSLTYNQLAVIYKLIWYQDGYEQPSEEDLR----RIMSQPDENESQ----------TDVSFRH-I 463
            ....:..|..|..:           :.|:|    .|:.:|.....|          |:|...| |
 Worm   151 SEGDHKLLQTITDM-----------DTDIRTRTAHILGEPANGNEQIHFYSPTPDYTNVIVNHGI 204

  Fly   464 TEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYT 528
            .....:.:.|:.|:...:|.|.::.:..|         :.:|.|...||......:|.| ...|.
 Worm   205 GPSLKVDILLLREWVDRIPGFRELSERFQ---------QHLMHRFCLRYTVIEHGLFTA-QMPYH 259

  Fly   529 RDSYKMAG---MADNIEDLLHFCRQMFSMKVDNVEYAL--LTAIVIFSDRPGLEKAQLVEAIQSY 588
            ::.:.::.   :....|:|....::..:.||.|.:..|  .|.::|......|.:.: .::::..
 Worm   260 KNVWFLSDRTCLVSEFENLPQEIKKHLTPKVINEQQLLASFTEMLIHEVADPLRRLK-PDSVEVA 323

  Fly   589 YIDTLRIYILNRHC-----GDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKL----PK 644
            .:.||  .:|...|     ||         .||..|:::::.:          ::||.:    ..
 Worm   324 TVKTL--MLLKPTCLREIDGD---------YLSTETDIKSVND----------VRNRVINGLYSH 367

  Fly   645 FLEEIWDVHAIPPSVQSHLQIT 666
            :::...|...:|..|...|.:|
 Worm   368 YIKNGMDPEQLPIRVSEILNLT 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	37/99 (37%)
		NR_LBD_EcR	420..652	CDD:132736	43/260 (17%)
nhr-105	NP_001021303.1	ZnF_C4	38..109	CDD:197701	32/70 (46%)
		NR_LBD	202..395	CDD:132726	39/220 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910