Protein Alignment EcR and nhr-19

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_496066.2
• Gene: nhr-19 / 174512
• WormBaseID: WBGene00003618
• Length: 477
• Species: Caenorhabditis elegans
• Alignment Length: 429
• Identity: 94/429 - (21%)
• Similarity: 160/429 - (37%)
• Gaps: 136/429 - (31%)

  Fly   257 PRVQEE-----LCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKC 316
            |.|:.|     .||:||:.::|.||..:.|.|||.||||:|.:.....||..:.|::....|:.|
 Worm    68 PSVKPEKGVIGQCLICGEPSTGKHYGIVACLGCKTFFRRAVVQRQDTECKREKPCDVTTMARKAC 132

  Fly   317 QECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQ----- 376
            :.||.:|||..||..|.:.|.......||.:..........|.|..|       .....|
 Worm   133 RACRYRKCLESGMSKEALQPRRDLIGCRRIRSRPSCSTSTPTPPRPQ-------VEDKSQYLTLL 190

  Fly   377 -------DFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNI-----PSLTYNQLAVIYKLIW 429
                   |.::|:.|:::.   .:.|.:.|   .:|||....:|     ||.:.
 Worm   191 ENLTTIDDRLRKKKLEVVA---SRQAAVDL---AVLAKQGCMSITDTSGPSTSR----------- 238

  Fly   430 YQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQIT 494
            |..|...|:..|.:.::.      ..||:|....:|:.     :::|:.:.||.|..:|.:|:..
 Worm   239 YVPGGTSPNGGDHKMMVM------LGTDISVSTQSELL-----MMLEWTRTLPVFASLPVQDRSV 292

  Fly   495 LLKACSSEVMMLRMARRYDH-------SSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFC---- 548
            :||..:...::|      :|       :.|.::...|.:.         |..|:|.|...|
 Worm   293 ILKRFAVHCLIL------EHGYYTAQANIDDVWLITNGTC---------MPRNVEKLEEGCKISV 342

  Fly   549 ------------RQMFSMKVDNV------------EYALLTAIVIF-----SDRPGLEKA----- 579
                        :||....:|.|            |..::..||:|     ||...:.:|
 Worm   343 SADRRWRQEKLYKQMTDCCIDEVATPLRNLKLSPQEIVVIKIIVLFNCGCSSDYSEITEASRRIV 407

  Fly   580 -----QLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAK 613
                 ::|.|:.:||              :|:.|..||:
 Worm   408 LTFRNKVVSALFAYY--------------ESVGLQNYAE 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	33/94 (35%)
		NR_LBD_EcR	420..652	CDD:132736	44/244 (18%)
nhr-19	NP_496066.2	NR_DBD_HNF4A	80..155	CDD:143518	30/74 (41%)
		HOLI	268..447	CDD:214658	37/199 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165622
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840