Protein Alignment EcR and nhr-21

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_001040766.1
• Gene: nhr-21 / 174202
• WormBaseID: WBGene00003620
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 467
• Identity: 106/467 - (22%)
• Similarity: 178/467 - (38%)
• Gaps: 127/467 - (27%)

  Fly   264 CLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVG 328
            |.||||.|.|.||....|.|||||||||:.|:..|.|::...|.:....|..|:.||||:|:.||
 Worm    30 CAVCGDTALGKHYGVTACNGCKGFFRRSIWKNRTYACRYQGKCGVAKEQRNACRSCRLKECIKVG 94

  Fly   329 MRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMT----- 388
            |.|..|               |.:.|..:||.:|.     :|.|.....:.|.|.::..|
 Worm    95 MNPRAV---------------QGDIDTASTSSASP-----NLVSVEMHPYTKSEEVECQTEVSTI 139

  Fly   389 -CEPPQHATIPLLPD-----EILAKCQARNIPSLTYNQLAVI----------YKLIWYQDGYEQP 437
             ..|...:|:|.:..     .:.:.|.  ::.::..|.||::          |.|
 Worm   140 SSHPTSPSTLPFVSSGSSICSVSSSCS--SVSTVYSNCLAMLPPNPSLPKYDYLL---------- 192

  Fly   438 SEEDLRRIMSQPDENESQ---TDVSFRHI----------TEIT-----ILTVQ-----------L 473
              ..|.||..:.||:..:   ...||.|.          |::|     |.|:.           |
 Worm   193 --ASLSRIFERVDEHAPEPLPNTYSFEHAFYNPHLICNRTKLTPTGERIATLPEVLQDFRRIFVL 255

  Fly   474 IVEFAKGLPAFTKIPQEDQITLLKA-CSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMA-- 535
            ..:....||.|:::.:.|::.|.|: .|.....|............:.:||...:..|..:.|
 Worm   256 FTDVLSILPEFSRLDESDRMVLAKSRFSFFYWWLTCCWTAKVGCPGVCYANGAYHPSDKRQQAFP 320

  Fly   536 -----GMAD-NIEDLLHFCRQMFSMKVDNVEYALLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLR 594
                 |:.: ::|.:   .:.:.::.:.:.|..:.:...||.:.|...|..        |..|
 Worm   321 DVNYRGVTELSVETV---SKPLANINITDAEMLVGSVFAIFYEYPLPPKVS--------YAST-- 372

  Fly   595 IYILNR------HCGDSMS------------LVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRK 641
             :|||.      .|..::|            |...:.:.|.:|.|:.|.:.|.|:  |..|...:
 Worm   373 -HILNEARDLYTQCMITVSPYSQLEAKSASRLAEISLIFSSITNLKYLTSDNIEL--SDVLHVME 434

  Fly   642 LPKFLEEIWDVH 653
            :.:.:.|.:|||
 Worm   435 VDQLITEAFDVH 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	35/86 (41%)
		NR_LBD_EcR	420..652	CDD:132736	53/297 (18%)
nhr-21	NP_001040766.1	NR_DBD_HNF4A	30..105	CDD:143518	36/89 (40%)
		NR_LBD	244..416	CDD:132726	30/185 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165648
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840