Protein Alignment EcR and Nr1i3

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_033933.2
• Gene: Nr1i3 / 12355
• MGIID: 1346307
• Length: 358
• Species: Mus musculus
• Alignment Length: 408
• Identity: 120/408 - (29%)
• Similarity: 194/408 - (47%)
• Gaps: 78/408 - (19%)

  Fly   248 AKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYM 312
            |.:.:.||      ..|:||||||:|||::|||||||||||||:|:|:....|.|...||:....
Mouse    11 ASEEEYGP------RNCVVCGDRATGYHFHALTCEGCKGFFRRTVSKTIGPICPFAGRCEVSKAQ 69

  Fly   313 RRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQD 377
            ||.|..|||:|||.||||.:.::.....|: ||.::||:..:|.:...:.|
Mouse    70 RRHCPACRLQKCLNVGMRKDMILSAEALAL-RRARQAQRRAEKASLQLNQQ-------------- 119

  Fly   378 FVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDL 442
              :||::                  :||.....|::..: ::|. |.:|...|...:.:|
Mouse   120 --QKELV------------------QILLGAHTRHVGPM-FDQF-VQFKPPAYLFMHHRP----- 157

  Fly   443 RRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLR 507
                .||   .........|..:|....||.|::|.|.||.|..:..||||:|||..:.|::.:.
Mouse   158 ----FQP---RGPVLPLLTHFADINTFMVQQIIKFTKDLPLFRSLTMEDQISLLKGAAVEILHIS 215

  Fly   508 MARRYDHSSDSIFFANNRSYTRDSYKMAGMA-DNIEDLLHFCRQMFSMKVDNVEYALLTAIVIFS 571
            :...:...::: ||.....|..:....||.. :.:|.:|||.:.:..:.:...||.|:.|..:||
Mouse   216 LNTTFCLQTEN-FFCGPLCYKMEDAVHAGFQYEFLESILHFHKNLKGLHLQEPEYVLMAATALFS 279

  Fly   572 -DRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLV----FYAKLLSILTELRTLGNQNAEM 631
             ||||:.:.:.::.:|..     ...|||.|..:..|.:    .||||:.:|.:||::.|
Mouse   280 PDRPGVTQREEIDQLQEE-----MALILNNHIMEQQSRLQSRFLYAKLMGLLADLRSINN----- 334

  Fly   632 CFSLKLKNRKLPKFLEEI 649
            .:|.:|:.      |||:
Mouse   335 AYSYELQR------LEEL 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	46/89 (52%)
		NR_LBD_EcR	420..652	CDD:132736	63/236 (27%)
Nr1i3	NP_033933.2	NR_DBD_VDR_like	21..92	CDD:143531	42/70 (60%)
		NR_LBD	116..356	CDD:299703	69/296 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010