Protein Alignment EcR and ppard

DIOPT Version :10

• Sequence 1: NP_724460.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: XP_031752685.1
• Gene: ppard / 100038152
• XenbaseID: XB-GENE-481495
• Length: 398
• Species: Xenopus tropicalis
• Alignment Length: 440
• Identity: 121/440 - (27%)
• Similarity: 196/440 - (44%)
• Gaps: 70/440 - (15%)

  Fly   230 DLSPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTK 294
            ::.|.|...|    |.....:..:..:.||.   |.:|||||||:||....||||||||||::..
 Frog     6 EIPPHSPFLG----EQLSTPQEHQETSQRVN---CKICGDRASGFHYGVHACEGCKGFFRRTIRM 63

  Fly   295 SAVY--CCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMT 357
            ...|  |   .|.|::....|.|||.||..|||::||....:         |..:..:.||.|:.
 Frog    64 RLQYENC---DRNCKIQKKNRNKCQYCRFNKCLSLGMSHNAI---------RFGRMPESEKRKLV 116

  Fly   358 TSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLA 422
            .:|.:......|..|            ||.......|::  .:....:.|.:||:|  ||.....
 Frog   117 QAPVTDSAAPDSPVS------------DLDALSQLIHSS--YMNTFTMTKKRARDI--LTGRSTI 165

  Fly   423 ---VIYKL--IWYQDG---YEQPSEEDLRRIMSQPDENESQTDVS---FRHITEITILTVQLIVE 476
               ||:.:  :|..:.   :||...:||           :.|::.   |......::.||:.:.:
 Frog   166 TPFVIHDMDTLWQAEQGTVWEQLPTQDL-----------TGTEIGVHVFYRCQCTSVETVRALTD 219

  Fly   477 FAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSY-TRDSYK--MAGMA 538
            |||.:|.|:.:...||:||||....|.:...:|...  :.|.:..|..|.: ||:..:  .....
 Frog   220 FAKSVPGFSTLYLNDQVTLLKYGVHEAIFCMLASLM--NKDGLLVAGGRGFVTREFLRSLRQPFC 282

  Fly   539 DNIEDLLHFCRQMFSMKVDNVEYALLTA-IVIFSDRPGLEKAQLVEAIQSYYIDTLRIYILNRHC 602
            ..:|...||..:..::::::.:.||..| |::..|||||.....||.||...:..||.::...|.
 Frog   283 HIMEPKFHFASKFNALELNDSDLALFVASIILCGDRPGLINPSQVEDIQEGILGALRRHLKTSHT 347

  Fly   603 GDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKL--KNRKLPKFLEEIW 650
             |:..|  :.|||..:.:||.|..::||:..|:|.  .:..|...|:||:
 Frog   348 -DAPFL--FPKLLHKMADLRQLVTEHAELVQSIKRTESSAALHPLLQEIY 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_724460.1	NR_DBD_EcR	261..351	CDD:143535	36/91 (40%)
		NR_LBD_EcR	420..652	CDD:132736	64/248 (26%)
ppard	XP_031752685.1	NR_DBD_Ppar	33..115	CDD:143523	38/93 (41%)
		NR_LBD_PPAR	131..397	CDD:132730	74/296 (25%)