Protein Alignment Ars2 and srrt

DIOPT Version :10

• Sequence 1: NP_610203.2
• Gene: Ars2 / 35539
• FlyBaseID: FBgn0033062
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: XP_031753813.1
• Gene: srrt / 549806
• XenbaseID: XB-GENE-5825634
• Length: 875
• Species: Xenopus tropicalis
• Alignment Length: 1021
• Identity: 403/1021 - (39%)
• Similarity: 542/1021 - (53%)
• Gaps: 225/1021 - (22%)

  Fly     1 MGDSDDEYDRKRRDKFRGERESY-RTERRDDRRPVGGSAGARDEWAERNPFRGGASAGGGGARHR 64
            |.||||||||:||||||.||..| |:..|::||        ||:|::|...||..      .|.|
 Frog     1 MADSDDEYDRRRRDKFRRERSDYDRSREREERR--------RDDWSDREWDRGRE------RRSR 51

  Fly    65 PDYSDYRGPGARPRYGSPVRDL-PPAKRMRPDWGDGDVRANPRFGGYD-PYLM----------QA 117
            .:|.||.....|.|:.....|| ||.||||.||.|..  ::|...||| ||..          |.
 Frog    52 GEYRDYESRSRRERFSPQRHDLSPPQKRMRRDWDDHG--SDPYHSGYDMPYSSAAGGPGYGPPQP 114

  Fly   118 WNDHYQSMHSAYSHGGHAPPVRESIGGGGGDTLTQPA--MLNLKQFLDTQDENISDSEVMRKYTE 180
            |.  :..:|....||   .|::..:|......|..||  |...|:||.:.::::.::|.:::|.:
 Frog   115 WG--HPEIHVMQHHG---IPIQARLGNLHEVDLGTPAPIMKTFKEFLLSLEDSVDETEAVKRYND 174

  Fly   181 YKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVD 245
            ||.||:|||:.|||:||||||||::||||::..|..:|.:..|:.|...||.|:||..:..|::|
 Frog   175 YKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESQAALRNRLSAFMYLMENSWLNEVQLD 239

  Fly   246 SSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSE 310
            .:|:.|:|:|||..|||:||||:.|||:|||:.::......|.|:.::. |.||.:...||..::
 Frog   240 IAQSTAIIKVLDAAVIKMEGGTEIDLKILDEEEEEAKREAAKKEEARAT-EAEKKVTEEKEPPAK 303

  Fly   311 AD---PVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRN 372
            .:   ...|:.|||:|        ::::.|....|:|           || ::..|..|:||||:
 Frog   304 PEKDKEAETEEKPVKP--------EEEEEEKKVEKEE-----------PE-RETRKPGTRKRKRS 348

  Fly   373 SSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNEN 437
            ...||.|.|||.:.:                                     .|||
 Frog   349 GDSDDGSDSESDTET-------------------------------------ASPK--------- 367

  Fly   438 TEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDK 502
              ||                     :..|.:|....|..|.||:.||.   |:|..|      |.
 Frog   368 --PK---------------------AETPSQNGRAEDTPKKEEETEKQ---KEKQKE------DP 400

  Fly   503 VKDGQPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDV 567
            ||   ||.||:|.|||:||:.|:|:::||.|:|.|:.|::|||:::|..|||:.|:.::||.|.|
 Frog   401 VK---PRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSV 462

  Fly   568 NIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLW 632
            |||||||.:.|.|||:||:...|||||:.|||..||||.|:.:||:||||.|::...|||:..||
 Frog   463 NIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITMHRPIVRNDIKLAARLIHALDERALLW 527

  Fly   633 AEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLGLTGENKDT--- 694
             ||.:.|..                 .::|||:|:|||||||:|.:|||||||...|...:|
 Frog   528 -EGEQGDQM-----------------VSAQNPILKNITDYLIDEVNAEEEELLFSAGRTPETETP 574

  Fly   695 -EGEP----IERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGP-PPVRV 753
             ||.|    :||||:||.|||:|:.||||||||||||.||||.|||||.|||::|.||| ||.||
 Frog   575 KEGNPTEISVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRGPLPPNRV 639

  Fly   754 TNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSG 818
            ::.:|.|:.|.:|.||.........||:||...:|.||.|.||||||.||||||.|:||||||||
 Frog   640 SHGEVAEWQKTFEEKLSPLFAVRETLSEEEAVKMGKKDPEQEVEKFVTANTQELGKEKWLCPLSG 704

  Fly   819 KKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPE----HPGTSKRPESESARGG 879
            ||||||||:||||||||.||::||:|||.:|||||.|.|||.|||    .|     |...:.:..
 Frog   705 KKFKGPEFVRKHIFNKHGEKIEEVKKEVAFFNNYLIDSKRPALPEVKPLQP-----PVGTAGQAL 764

  Fly   880 GGGYRPPMYPPFSAMPYG--------------FGPPMMGGGRG------GRNFPPA--RRELPL- 921
            ..|...|...|.:.:||.              |.|...|.|||      |:...|.  |..|.|
 Frog   765 AAGLLYPHQGPQALLPYAQPRPPVLGYAGAPQFPPTPYGAGRGNYDAFRGQGMYPGKPRNRLALS 829

  Fly   922 -------------EHQ------------RRLIGYHDLDAPANSDMF 942
                         .|.            |.:|.|.|||||.:.:.|
 Frog   830 LPSSILPTCLSVPSHSSSPPRRMIRGDPRAIIEYRDLDAPDDVEFF 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ars2	NP_610203.2	SERRATE_Ars2_N	159..268	CDD:463453	50/108 (46%)
		ARS2	746..896	CDD:461498	82/154 (53%)
srrt	XP_031753813.1	SERRATE_Ars2_N	153..262	CDD:463453	50/108 (46%)
		RRM	411..>459	CDD:214636	22/47 (47%)
		ARS2	631..824	CDD:461498	92/197 (47%)