DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SmydA-5 and SDG37

DIOPT Version :9

Sequence 1:	NP_610202.3	Gene:	SmydA-5 / 35538	FlyBaseID:	FBgn0033061	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_849969.2	Gene:	SDG37 / 816300	AraportID:	AT2G17900	Length:	485	Species:	Arabidopsis thaliana

Alignment Length:	526	Identity:	122/526 - (23%)
Similarity:	195/526 - (37%)	Gaps:	106/526 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 GRYLKVTQNIAAGQIVFIEEPLVVGPKWYLSDADKEASNVPCVGCYTPCRLGKHQCRRCR--WPV 117
            ||.|...::...|:::..::|.:..|       :..:|...|.||:....|.|  |..|:  | .
plant    27 GRSLFTARDFRPGEVILSQKPYICVP-------NNTSSESRCDGCFKTNNLKK--CSACQVVW-Y 81

  Fly   118 CSAGCKHESM-----ECSVLSLGSGSPTRADARSLNDYFRGDALLVLKCLLLQRQ---------- 167
            |.:.|:....     ||..|       ||.:.....  |....:.::..|.::|.
plant    82 CGSSCQKSEWKLHRDECKAL-------TRLEKEKRK--FVTPTIRLMVRLYIKRNLQNEKVLPIT 137

  Fly   168 SPTKWSALLEMQSHEEERKGTDLYEEAEKRVVTYLQKRFLCRLKQTNPNL-LTDCGPEM------ 225
            :...:|.:..:.||        :.|..||:::.|.|...|..|....|:: |.:.....
plant   138 TTDNYSLVEALVSH--------MSEIDEKQMLLYAQMANLVNLILQFPSVDLREIAENFSKFSCN 194

  Fly   226 LHRLCGIIETNFMVIEL-PSGVELSGLFRQACMMEHACQPNCDFQFDNKTQQVAVRAGCDLRKGD 289
            .|.:|.        .|| |.|:   |||....::.|:|.||....|:.  |...|||..::.|..
plant   195 AHSICD--------SELRPQGI---GLFPLVSIINHSCSPNAVLVFEE--QMAVVRAMDNISKDS 246

  Fly   290 HLRITYTNILWGTQLRQHHLRLTKHFSCRCSRCLD-----PTEYGTYISALTCLGDVNQTCGGTH 349
            .:.|:|......|..||..|:....|.|:|:||.:     ..|....:....|   .|:.|.| .
plant   247 EITISYIETAGSTLTRQKSLKEQYLFHCQCARCSNFGKPHDIEESAILEGYRC---ANEKCTG-F 307

  Fly   350 LPVDPLDENTQWKCDTCPMIVDGAYVAELQSHMTEQVEGLLAGCPSA--NQVELLLARLTHMLHP 412
            |..||  |...:.|..|.::.....|.:|.|.: :.|.......|||  .|..:.|.:....|..
plant   308 LLRDP--EEKGFVCQKCLLLRSKEEVKKLASDL-KTVSEKAPTSPSAEDKQAAIELYKTIEKLQV 369

  Fly   413 NHFHTFN--LKHTLIQLYGNEAGLELGVLSNTQLERKLRLCGELYNVCRRLDPYSIKLAIY-VTV 474
            ..:|:|:  |..|..:|        |.:|.:.::.|      |..|.||.:.|  :...:| .|.
plant   370 KLYHSFSIPLMRTREKL--------LKMLMDVEIWR------EALNYCRLIVP--VYQRVYPATH 418

  Fly   475 ILIEVAHTLQ---EQARRAPAEGTSLLGLAQSRLREAHMVLEKEQESVAGKKLNEKLQMEIFECE 536
            .||.:....|   |.......|..|.|..|...||.:|.:     .:...|:|:.||:....|..
plant   419 PLIGLQFYTQGKLEWLLGETKEAVSSLIKAFDILRISHGI-----STPFMKELSAKLEEARAEAS 478

  Fly   537 KLILAL 542
            ...|||
plant   479 YKQLAL 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-5	NP_610202.3	zf-MYND	7..43	CDD:280009
SmydA-5	NP_610202.3	SET	185..295	CDD:279228	29/117 (25%)
SDG37	NP_849969.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	60	1.000	Domainoid score	I3856
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820