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Protein Alignment SmydA-5 and SMYD3

DIOPT Version :9

Sequence 1:	NP_610202.3	Gene:	SmydA-5 / 35538	FlyBaseID:	FBgn0033061	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_001161212.1	Gene:	SMYD3 / 64754	HGNCID:	15513	Length:	428	Species:	Homo sapiens

Alignment Length:	482	Identity:	93/482 - (19%)
Similarity:	143/482 - (29%)	Gaps:	192/482 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CPVC--GVAASQACTRCKMVRYCDREHQKQHWPQHKRRCRPFSEEQDAELGRYLKVTQNIAAGQI 69
            |..|  |......|::|::.:||..:.||:.||.|||.|:
Human    49 CDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECK------------------------- 88

  Fly    70 VFIEEPLVVGPKWYLSDADKEASNVPCVGCYTPCRLGKHQCRRCRWPVCSAGCKHESMECSVLSL 134
                                                            |...||......||..|
Human    89 ------------------------------------------------CLKSCKPRYPPDSVRLL 105

  Fly   135 G-------SGSPTRADA------------RSLNDYFRGDALLVLKCLLLQRQSPTKWSALLEMQS 180
            |       .|:|:.::.            :...|...|...||:......|:         |:|.
Human   106 GRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMRE---------EIQD 161

  Fly   181 HEEERKGTDLYEEAEKRVVTYLQKRFLCRLKQTNPNLLTDCGPEMLHRLCGIIETNFMVIELPSG 245
            ..:.....||:|...|         .:|       |..|.|..||..                .|
Human   162 ASQLPPAFDLFEAFAK---------VIC-------NSFTICNAEMQE----------------VG 194

  Fly   246 VELSGLFRQACMMEHACQPNCDFQFDNKTQQVAVRAGCDLRKGDHLRITYTNILWGTQLRQHHLR 310
            |   ||:....::.|:|.|||...|:.  ..:.:||..|:..|:.|.|.|.::|..::.|:..||
Human   195 V---GLYPSISLLNHSCDPNCSIVFNG--PHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLR 254

  Fly   311 LTKHFSCRCSRCLDPTEYGTYISALTCLGDVNQTCGGTHLPVDPLDENTQWKCDTCPMIVDGAYV 375
            ....|.|.|.||....:            |.:...|         ||.. ||    .:......:
Human   255 DQYCFECDCFRCQTQDK------------DADMLTG---------DEQV-WK----EVQESLKKI 293

  Fly   376 AELQSHMT-EQVEGLLAGCPSANQVELLLARLTHMLHPNHFHTFNLKHTLIQLYGNEAGLELGVL 439
            .||::|.. |||..:.....|:|...|          |:    .|:....:.....:|.:.||:|
Human   294 EELKAHWKWEQVLAMCQAIISSNSERL----------PD----INIYQLKVLDCAMDACINLGLL 344

  Fly   440 SNTQLERKLRLCGELYNVCRRLDPYSI 466
            ...           |:...|.::||.|
Human   345 EEA-----------LFYGTRTMEPYRI 360

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.