Protein Alignment SmydA-5 and Smyd3

DIOPT Version :10

• Sequence 1: NP_610202.3
• Gene: SmydA-5 / 35538
• FlyBaseID: FBgn0033061
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_524768.2
• Gene: Smyd3 / 44554
• FlyBaseID: FBgn0011566
• Length: 468
• Species: Drosophila melanogaster
• Alignment Length: 575
• Identity: 117/575 - (20%)
• Similarity: 186/575 - (32%)
• Gaps: 189/575 - (32%)

  Fly     5 TECPVCGVAASQ----------------ACTRCKMVRYCDREHQKQHWPQHKRRCRPFSEEQDAE 53
            ||.|...|..||                .|:.|:.|.||.|..|.|.|.|||..| ||.:
  Fly    43 TEKPFAFVLKSQYRLERCDNCLEATKVLKCSNCRYVSYCHRSCQMQAWGQHKHEC-PFLK----- 101

  Fly    54 LGRYLKVTQNIAAGQIVFIEEPLVVGPKWYLSDADKEASNVPCVGCYTPCRLGKHQCRRCRWPVC 118
                 ||             .|.||      .||.:..           |||
  Fly   102 -----KV-------------HPRVV------PDAARML-----------CRL------------- 118

  Fly   119 SAGCKHESMECSVLSLGSGSPTRADARSLNDYFRGDALLVLKCLLLQRQSPTKWSALLEMQSHEE 183
                        :|.|..|          .|..||         ........|:.   ::.||..
  Fly   119 ------------ILRLEHG----------GDLIRG---------YYTEHGSRKFR---DLMSHYA 149

  Fly   184 ERKGTDL---YEEAEKRVVTYLQKRFLCRLKQTNPNLLTDCGPEMLHRLCGIIETNFMVIELPSG 245
            |.|...:   :.::...|:|.:    :.....|.||     ..|::.....:|...|.:::....
  Fly   150 EIKNDPMRLEHLDSLHAVLTDM----MAESPSTVPN-----KTELMSIYGRLITNGFNILDAEMN 205

  Fly   246 VELSGLFRQACMMEHACQPNCDFQFDNKTQQVAVRAGCDLRKGDHLRITYTNILWGTQLRQHHLR 310
            ...:.::....:.:|:||||....|:.....|......:......:.|:|.::|...:.|:..|:
  Fly   206 SIATAIYLGVSITDHSCQPNAVATFEGNELHVHAIEDMECLDWSKIFISYIDLLNTPEQRRLDLK 270

  Fly   311 LTKHFSCRCSRCLDPTEYGTYISALTCLGDVNQTCGGTHLPVDPLDENTQWKCDT--CPMIVDGA 373
            ...:|.|.||:|.|..|....::|| |   .|:.||..    ..:|.|...:||.  .|.:.:..
  Fly   271 EHYYFLCVCSKCTDAKESKEMLAAL-C---PNRNCGAG----ISVDRNNCPRCDAGISPKLRNAF 327

  Fly   374 YVA-ELQSHMTEQVEGL--LAGCPSANQVELLLARLTHMLHPNHFHTFNLKHTLIQLYGNEAGLE 435
            ..| .|..|..|.::.:  |..|      ::.|.:.|.:.||  .:.:.:| ||...:  ||.:|
  Fly   328 NEAMTLTRHNLENMKDVAYLDVC------KVCLDKQTGVFHP--LNVWYVK-TLDAAF--EAAIE 381

  Fly   436 LGVLSNTQLERKLRLCGELYNVCRRLDPYSIKLAIYVTVILIEVAHTLQEQARRAPAEGTSLLGL 500
            :|..|:.                                  ::....|....|:.......||||
  Fly   382 VGKWSDA----------------------------------LDYGQRLLPGFRKYHGPWNPLLGL 412

  Fly   501 AQSRLREAHMVLEKEQ--ESVAGKKLNEKLQMEIFECEKLILALAYNQDHEANTK 553
                   .||.|.|.|  |.      :.|..:...|..:.||.:.:.:||...|:
  Fly   413 -------LHMKLGKIQLYEG------HSKEALHHLEEAQRILTVTHGRDHRLLTE 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-5	NP_610202.3	zf-MYND	7..43	CDD:460312	16/51 (31%)
		SET_SMYD	<232..322	CDD:380997	18/89 (20%)
Smyd3	NP_524768.2	SET	34..284	CDD:394802	67/337 (20%)
		zf-MYND	60..97	CDD:460312	12/36 (33%)
		TPR_12	<383..441	CDD:315987	16/104 (15%)