DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-5 and Smyd5

DIOPT Version :9

Sequence 1:	NP_610202.3	Gene:	SmydA-5 / 35538	FlyBaseID:	FBgn0033061	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_650955.1	Gene:	Smyd5 / 42517	FlyBaseID:	FBgn0038869	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	374	Identity:	79/374 - (21%)
Similarity:	133/374 - (35%)	Gaps:	115/374 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 GRYLKVTQNIAAGQIVFIEEPLVVGP-KWYLSDADKEASNVPCVGCYTPCR-------------- 104
            ||.:..|:|.|..:::|.|||.|... .|.::     .....|..|..|..
  Fly    13 GRAMIATKNFAKDEVIFEEEPFVSRQFSWNVA-----YGYAACDHCMRPLETVLENVRRLASDPK 72

  Fly   105 ----LGKH-----------QCRRCRWPVCSAGCKHESME--CSVLSLGS-GSPTRADARSLNDYF 151
                |.:|           ||.||:...||..|..|:.:  ..|..:|: .|........||:.:
  Fly    73 VEVPLLQHDPTAQWVAQFTQCPRCKVRYCSEDCLMEAQKRYHRVACMGAFHSDDTHPINVLNETW 137

  Fly   152 R--------GDALLVLKCLLLQRQSPTKWSALLEMQSHEEERKGTDLYEEAEKRVV-TYLQKRFL 207
            :        |..:|:::.:.|.:||..|...|.::||.:      .|....|:::. ..|.:.|.
  Fly   138 KKMHYPPETGSIMLIVRLMALYQQSTKKEEFLEQLQSFQ------SLIVNREQKIYHKMLGENFE 196

  Fly   208 CRLKQTNPNLLTDCG------------PEMLHRLCGIIETNFM-------------VIELP---- 243
            .:::|.   .|..|.            |:....|..|:.||..             |.:||
  Fly   197 QQMEQL---YLAFCNAFTGEEFSIFKTPDAFKTLMAILGTNSQGIATSVLSQWVAKVSDLPLTDS 258

  Fly   244 ---------SGV--------------ELSGLFRQACMMEHACQPNCDFQFDNKTQQVAVRAGCDL 285
                     .|:              |.|||:.....:.|:|.||....|......|.::|...:
  Fly   259 EKEQLDTVIDGLYAKVGEFAGEFLNNEGSGLYLLQSKINHSCVPNACSTFPYSNDIVVLKALAPI 323

  Fly   286 RKGDHLRITYTN--ILWGTQLRQHH-LRLTKHFSCRCSRC----LDPTE 327
            ::|:.:.|:|.:  :|..::..:|. ||....|.|:|.:|    .||.|
  Fly   324 QQGEEICISYLDECMLERSRHSRHKVLRENYVFICQCPKCRAQASDPDE 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-5	NP_610202.3	zf-MYND	7..43	CDD:280009
SmydA-5	NP_610202.3	SET	185..295	CDD:279228	29/162 (18%)
Smyd5	NP_650955.1	zf-MYND	87..118	CDD:280009	9/30 (30%)
Smyd5	NP_650955.1	SET	<296..333	CDD:279228	9/36 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452048
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830