DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-5 and SmydA-7

DIOPT Version :9

Sequence 1:	NP_610202.3	Gene:	SmydA-5 / 35538	FlyBaseID:	FBgn0033061	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_001261039.1	Gene:	SmydA-7 / 36916	FlyBaseID:	FBgn0034182	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	510	Identity:	155/510 - (30%)
Similarity:	230/510 - (45%)	Gaps:	66/510 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 DAELGRYLKVTQNIAAGQIVFIEEPLVVGPKWYLSDADKEASNVPCVGCYTPCRLGKHQCRRCR- 114
            |.:|||:|..:..|..|..:..|.||:|.|.|       |...:.|..|.....:   .||||:
  Fly    13 DEKLGRHLVASIAIEPGDTILEERPLLVAPHW-------ECHQLKCAQCLQESYV---ICRRCQV 67

  Fly   115 WPVCSAGCKHESMECSVLSLGSGSPTRADARSLNDYFRGDALLVLKCLLLQRQSPTKWSA--LLE 177
            :|:|....:|:..||...:.|:|.....|....|....|    :||.|||.....||...  |::
  Fly    68 FPLCMDCNQHDEFECEFFTSGAGKALCKDILVKNFGICG----LLKLLLLLENPRTKGDCQMLID 128

  Fly   178 MQSH-EEERKGTDLYEEAEKRVVTYLQKRFLCRLKQTNPNLLTDCGPEMLHRLCGIIETNFMVIE 241
            :..: .:.|.|..:::|.|:.||..|.:..|..:..|. .|.:|.    ||..|..|::|...:.
  Fly   129 VPINLSDYRDGEGMWQEHEELVVRPLMESGLADVLPTQ-ELTSDA----LHAHCIRIDSNSFEVT 188

  Fly   242 LPSGVELSGLFRQACMMEHACQPN----CDFQFDNKTQQVAVRAGCDLRKGDHLRITYTNILWGT 302
            ...|..|.|:|.....:.|.|.||    .|.||:.|     :.|...|:.||.:..:|||.|.||
  Fly   189 AKDGDTLKGIFVWGATLPHHCVPNTVVALDEQFNMK-----LYAAVPLQPGDIIYNSYTNPLMGT 248

  Fly   303 QLRQHHLRLTKHFSCRCSRCLDPTEYGTYISALTCLGDVNQTCGGTHLPVDPLDENTQ---WKCD 364
            ..|||.|||::...|.|||||||||.||::|:|.|     :.|.|  ..|..:|.|.:   |:|.
  Fly   249 SQRQHQLRLSRRLECICSRCLDPTEMGTHMSSLKC-----KECPG--FSVCEIDSNGKLGDWRCP 306

  Fly   365 TCPMIVDGAYVAELQSHMTEQVEGLLAGCPSANQV-ELLLARLTHMLHPNHFHTFNLKHTLIQLY 428
            .|..::..|.|.|||:    .|...|.......|| |.||.:...:||||||...::|..:..:
  Fly   307 DCRALLTAAEVHELQA----AVGSALVDAMGDLQVYEALLTQYGPLLHPNHFMLLDIKQNIASI- 366

  Fly   429 GNEAGLELGVLSNTQ-------LERKLRLCGELYNVCRRLDP-----YSIKLAIYVTVILIEVAH 481
                 |....|.|:.       |.|::.||.:|..|||.:.|     |:|.|..|: :.|:|:..
  Fly   367 -----LRAAALMNSMDQPCKKLLARRVELCSDLLPVCRAVVPGISKLYAIGLFEYL-LALVELVE 425

  Fly   482 TLQEQARRAPAEGTSLLGLAQSRLREAHMVLEKEQESVAGKKLNEKLQMEIFECE 536
            ....::..:..|..:.|..|.....||..:|..|.|:.|...|.:::.||:...|
  Fly   426 LQFAESDLSKKEYVAHLRTASLVATEAMDLLRFEPENSAEGYLADRISMELERIE 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-5	NP_610202.3	zf-MYND	7..43	CDD:280009
SmydA-5	NP_610202.3	SET	185..295	CDD:279228	32/113 (28%)
SmydA-7	NP_001261039.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452049
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46455
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2203
	6	5.850