DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-5 and Smyd5

DIOPT Version :9

Sequence 1:	NP_610202.3	Gene:	SmydA-5 / 35538	FlyBaseID:	FBgn0033061	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_659167.2	Gene:	Smyd5 / 232187	MGIID:	108048	Length:	416	Species:	Mus musculus

Alignment Length:	360	Identity:	86/360 - (23%)
Similarity:	133/360 - (36%)	Gaps:	86/360 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 DAELGRYLKVTQNIAAGQIVFIEEPLVVGP-KW--------------YLSDADKEASNV---PCV 97
            |:..|:.|..||.|..|:.:|||.|||... .|              .|..|::.|..:   |..
Mouse    29 DSIKGKGLFATQLIRKGETIFIERPLVAAQFLWNALYQYRACDHCLRALEKAEENAQRLTGKPSQ 93

  Fly    98 GCYTP--CRLGK--HQ-CRRCRWPVCSAGCKHESME--CSVLSLGSGSPTRADARSLNDYFR--- 152
            ....|  |.:.|  || |..|:...|||.|:..:.|  ..:|..|.....|.....|.:.:|
Mouse    94 ILPHPELCSVRKDLHQNCPHCQVMYCSAECRLAAAEQYHQILCPGPSHDPRHPLNKLQEAWRSVH 158

  Fly   153 -----GDALLVLKCLLLQRQSPTK--WSALL----EMQSHEEER------KG------------- 187
                 ...:|:.:.:...:|:..|  |..|.    ...:::|:.      ||
Mouse   159 YPPETASIMLMARMVATVKQAKDKDHWVRLFNHFCSRTANQEQAIVHKLLKGKFKDQLELLLGLF 223

  Fly   188 -TDLYEEAEKRVVTYLQKRFLCRLKQTNPNLL--------------TDCGPEMLHRLCGIIETNF 237
             ..|||||.....|....|.|..|..||...:              .:..|:...:|...|:..:
Mouse   224 KEALYEEALSLWFTPEGFRSLFALVGTNGQGIGTSSLSQWVHACDALELTPQDREQLDTFIDQLY 288

  Fly   238 MVIELPSG----VELSGLF-RQACMMEHACQPNCDFQFDNKTQQVAVRAGCDLRKGDHLRITYTN 297
            ..||..:|    .|.|||| .|:| ..|:|.||.:..|......:.|.|..|::.|:.:.|:|.:
Mouse   289 KDIEAATGEFLNCEGSGLFVLQSC-CNHSCVPNAETSFPENNFVLHVTALEDIKPGEEICISYLD 352

  Fly   298 ILWGTQLRQHHLRLTKH---FSCRCSRCL----DP 325
            .....:.|....::.:.   |:|.|.:||    ||
Mouse   353 CCQRERSRHSRHKILRENYLFNCSCPKCLAEADDP 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-5	NP_610202.3	zf-MYND	7..43	CDD:280009
SmydA-5	NP_610202.3	SET	185..295	CDD:279228	36/148 (24%)
Smyd5	NP_659167.2	SET	<297..350	CDD:214614	17/53 (32%)
Smyd5	NP_659167.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..416		2/5 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810