DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-5 and smyd1

DIOPT Version :9

Sequence 1:	NP_610202.3	Gene:	SmydA-5 / 35538	FlyBaseID:	FBgn0033061	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	XP_012811600.1	Gene:	smyd1 / 100145429	XenbaseID:	XB-GENE-978314	Length:	491	Species:	Xenopus tropicalis

Alignment Length:	300	Identity:	72/300 - (24%)
Similarity:	122/300 - (40%)	Gaps:	60/300 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 GRYLKVTQNIAAGQIVFIEEPLVVGPKWYLSDADKEASNVPCVGCYTPCRLGKHQ-----CRRCR 114
            ||.|:..:...||.|:|.|..       |.:......|:..|..|:      |.|     |.:|:
Frog    13 GRGLRAIRESWAGDIIFAEPA-------YSAVVFDNLSHSVCHSCF------KRQEKLLRCGQCK 64

  Fly   115 WP-VCSAGCKHESM-----ECSVLSLGSGSPT---RADARSLNDYFRGDALLVLKCLLLQRQSPT 170
            :. .|...|:.||.     ||..:.....:|.   |..||.|....|..:.|...||:
Frog    65 FAHYCDRTCQKESWANHKNECVAIKKAGKAPNENIRLAARILWRIEREGSGLTEGCLV------- 122

  Fly   171 KWSALLEMQSHEEERKGTDLYEEAEKRVVTYLQKRFLCRLKQTNPNLLTDCGPEMLHRLCGIIET 235
               ::.::|:|      .|.::||||.::....::||    :..|:.....|.:.:..:..:|..
Frog   123 ---SIDDLQNH------IDKFDEAEKGLLMEDVQKFL----EYWPSQSQQFGMQYISHIFSVISC 174

  Fly   236 NFMVIELPSGVEL--SGLFRQACMMEHACQPNCDFQFDN----------KTQ-QVAVRAGCDLRK 287
            |...:....|::.  .|:|...|:..|.|.|||...|:|          .|| ::.:||...:.|
Frog   175 NGFTLSDQRGLQAVGVGIFPNLCLANHDCWPNCTVIFNNGNHEAVRSMFHTQMRIELRALGKINK 239

  Fly   288 GDHLRITYTNILWGTQLRQHHLRLTKHFSCRCSRCLDPTE 327
            |:.|.::|.:.|..|:.|:..|:...:|.|.|..|...|:
Frog   240 GEELTVSYVDFLNLTEDRKAQLKKQYYFDCTCEHCTKKTK 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-5	NP_610202.3	zf-MYND	7..43	CDD:280009
SmydA-5	NP_610202.3	SET	185..295	CDD:279228	29/122 (24%)
smyd1	XP_012811600.1	zf-MYND	47..85	CDD:280009	10/43 (23%)
smyd1	XP_012811600.1	SET	<189..252	CDD:214614	18/62 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2289
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.040