DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7849 and PUS4

DIOPT Version :9

Sequence 1:	NP_610201.1	Gene:	CG7849 / 35537	FlyBaseID:	FBgn0033060	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_014107.1	Gene:	PUS4 / 855424	SGDID:	S000005236	Length:	403	Species:	Saccharomyces cerevisiae

Alignment Length:	268	Identity:	50/268 - (18%)
Similarity:	99/268 - (36%)	Gaps:	73/268 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 MNGILNVYKPSG-------MKVKH--VRNAILS-NICKGLNEMEQ------------RKPRKLQE 58
            ||||..:.||||       :|::|  .::.:.| .|.:...|.:|            ||.||:.:
Yeast     1 MNGIFAIEKPSGITSNQFMLKLQHALTKSQVFSKEIQRATAERKQQYEKQTGKKASKRKLRKVSK 65

  Fly    59 NISLLGTGTAADHVLHNIGEQTDLSDHLLSTGPRYLPRDLICTTVSSLGDHTSGVLLFGINRGAG 123
              ..:|.|...|.:                                     .||||:.||..|..
Yeast    66 --VKMGHGGTLDPL-------------------------------------ASGVLVIGIGAGTK 91

  Fly   124 QSSSIRKNRPVRVYHLIGHLGIATENNLPDSRVIMRSNHRHVSADRISSLAASM--QASHQRKMF 186
            :.::.... .|:||......|::|.:...:..::.:::.:|::.|.:.::....  |......::
Yeast    92 KLANYLSG-TVKVYESEALFGVSTTSGDVEGEILSQNSVKHLNFDDLKTVEEKFVGQLKQTPPIY 155

  Fly   187 ELCGVDLQTQEAYELACRGLLRPADDSQPVVYGIKLI--HFDRPHF------TLELHAINETQEY 243
            ....:|.:....|....:.|.|..:..|..:|.:|:.  ...|.|.      |.| .|::..:..
Yeast   156 AALKMDGKPLHEYAREGKPLPRAIEPRQVTIYDLKVFSDSLKRDHDYPLLRPTTE-EAVDTVKNL 219

  Fly   244 LATLVHDM 251
            .|.:::|:
Yeast   220 NANMLNDV 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7849	NP_610201.1	PseudoU_synth_hTruB2_like	18..292	CDD:211345	48/266 (18%)
PUS4	NP_014107.1	PseudoU_synth_TruB_4	3..331	CDD:211344	48/266 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0130
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770