DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7849 and trub2

DIOPT Version :9

Sequence 1:	NP_610201.1	Gene:	CG7849 / 35537	FlyBaseID:	FBgn0033060	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001011086.1	Gene:	trub2 / 496499	XenbaseID:	XB-GENE-996199	Length:	325	Species:	Xenopus tropicalis

Alignment Length:	306	Identity:	105/306 - (34%)
Similarity:	167/306 - (54%)	Gaps:	20/306 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AATVFKHMNGILNVYKPSGMKVKHVRNAILSNICKGLNEMEQRKPRKLQENISLLGTGTAADHVL 73
            |..||:.::|:..||||.|:..|.||:.:.:|:.|.||.::||.||   :.|..|..||...:.|
Frog     5 APGVFRTLHGLFAVYKPPGVHWKSVRDTVETNLLKELNALKQRPPR---QQIRFLPAGTEGSNGL 66

  Fly    74 HNIGEQTD-------LSDHLLSTGPRYLPRDLICTTVSSLGDHTSGVLLFGINRGAGQSSSIRKN 131
                |.|.       |:||:|..||.:  ..:...|...|...:|||.:.||..|......:..:
Frog    67 ----EVTRVPSAVPVLADHVLVKGPAF--THIRVGTGHRLDIQSSGVFVLGIGHGNKLLKDMYNS 125

  Fly   132 RPVRVYHLIGHLGIATENNLPDSRVIMRSNHRHVSADRISSLAASMQASHQRKMFELCGVDLQTQ 196
            ...|.|.:.|.||.|||:.....:.|.::.:.|::.:::..:.|.:|.::|:.:.....:|||:|
Frog   126 HFTRDYTVRGMLGKATEDFTELGKTIEKTTYDHITREKLERILAVIQGTNQKALITHSHLDLQSQ 190

  Fly   197 EAYELACRGLLRPADDSQPVVYGIKLIHFDRPHFTLELHAINETQEYLATLVHDMALDLRTVAHC 261
            |||:||.:|.|||...|.|::.||:.:.|..|.||||:..::|||:||..::|::.|:||:.|.|
Frog   191 EAYDLAVQGKLRPMVKSPPIILGIRCLEFSPPEFTLEIQCMHETQQYLRKMIHEIGLELRSSAVC 255

  Fly   262 SQLRCVRHAHFDVTDSLLRHAWHL---PGIIKNLRQQRD-ILRAHP 303
            :|:|..|...|.|..||||..|.|   .|.|:..|.|.: :.|.:|
Frog   256 TQVRRSRDGPFTVDCSLLRTQWDLGSIQGAIRECRAQTEGVSRGNP 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7849	NP_610201.1	PseudoU_synth_hTruB2_like	18..292	CDD:211345	98/283 (35%)
trub2	NP_001011086.1	PseudoU_synth_hTruB2_like	14..286	CDD:211345	97/280 (35%)
trub2	NP_001011086.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..325		3/10 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	88	1.000	Domainoid score	I7812
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41056
Inparanoid	1	1.050	168	1.000	Inparanoid score	I4029
OMA	1	1.010	-	-		QHG46022
OrthoDB	1	1.010	-	-		D1535798at2759
OrthoFinder	1	1.000	-	-		FOG0006468
OrthoInspector	1	1.000	-	-		otm48985
Panther	1	1.100	-	-	LDO	PTHR13195
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5437
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080