Protein Alignment CCHa2-R and QRFPR

DIOPT Version :10

• Sequence 1: NP_001356958.1
• Gene: CCHa2-R / 35535
• FlyBaseID: FBgn0033058
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_937822.2
• Gene: QRFPR / 84109
• HGNCID: 15565
• Length: 431
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 97/379 - (25%)
• Similarity: 183/379 - (48%)
• Gaps: 40/379 - (10%)

  Fly    60 YVPVLDRPETYIVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVP 124
            |.|.|.......:.:...|||.:.:.||..:..:..|.::||.:.|.:|.||||:|||:...|:|
Human    36 YTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIP 100

  Fly   125 VATIVYTQESWPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLR-KLQTKPLTVFTA 188
            |..:....::|.....:|::..|.:..::...:.|:|.::.||:..:|:|.: |.|......||.
Human   101 VTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTM 165

  Fly   189 V-MIWILAILLGMP--SVLFSDIKSYPVFTATGNMTI--EVCSPFRDPEYAKFMVAGKALVYYLL 248
            : ::|::|:::|.|  .|...:|| |.......::..  |..||.....|..|::    ::.:||
Human   166 LGVVWLVAVIVGSPMWHVQQLEIK-YDFLYEKEHICCLEEWTSPVHQKIYTTFIL----VILFLL 225

  Fly   249 PLSIIGALY------IMMAKRLHMSA--RNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICF 305
            ||.::..||      :.:.||:...:  |.:.|::.|..:|.:.||.:    |:|..|.:|.:|:
Human   226 PLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVI----MMVTVVALFAVCW 286

  Fly   306 FPYHVFELWYHFYPTAEEDFDE-----FWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRY 365
            .|:||..:... |...|:::|:     .:.:::|:||.    ||..||:....::..|:::....
Human   287 APFHVVHMMIE-YSNFEKEYDDVTIKMIFAIVQIIGFS----NSICNPIVYAFMNENFKKNVLSA 346

  Fly   366 LC-CICVKR-QPHLRQHSTATGMMDNTSVMSMRRSTY--VGGTA---GNLRASL 412
            :| ||..|. .|..|..::...||...:..|:|.:..  ..|.|   ||:...|
Human   347 VCYCIVNKTFSPAQRHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKL 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	79/310 (25%)
		TM helix 1	71..97	CDD:320593	5/25 (20%)
		TM helix 2	104..130	CDD:320593	12/25 (48%)
		TM helix 3	142..172	CDD:320593	6/29 (21%)
		TM helix 4	182..202	CDD:320593	6/22 (27%)
		TM helix 5	234..259	CDD:320593	7/30 (23%)
		TM helix 6	285..315	CDD:320593	10/29 (34%)
		TM helix 7	330..355	CDD:320593	7/24 (29%)
QRFPR	NP_937822.2	7tmA_QRFPR	46..343	CDD:320333	79/310 (25%)
		TM helix 1	47..73	CDD:320333	5/25 (20%)
		TM helix 2	80..106	CDD:320333	12/25 (48%)
		TM helix 3	118..148	CDD:320333	6/29 (21%)
		TM helix 4	161..182	CDD:320333	6/20 (30%)
		TM helix 5	211..236	CDD:320333	8/28 (29%)
		TM helix 6	266..296	CDD:320333	11/33 (33%)
		TM helix 7	311..336	CDD:320333	7/28 (25%)