DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCHa2-R and si:ch211-119o8.4

DIOPT Version :9

Sequence 1:	NP_001356958.1	Gene:	CCHa2-R / 35535	FlyBaseID:	FBgn0033058	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	XP_001920980.2	Gene:	si:ch211-119o8.4 / 799453	ZFINID:	ZDB-GENE-070912-15	Length:	354	Species:	Danio rerio

Alignment Length:	348	Identity:	73/348 - (20%)
Similarity:	135/348 - (38%)	Gaps:	62/348 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 IVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNT-YILSLALADLLVILVCVPVATIVYTQES 134
            ::.::..|..:|||.|:..:.::..|:...|:.|:: .:|:|:.|||..:|. :|...:..:.::
Zfish    23 VLPLVSILSLLVGVGGHLLMWLVLMRNPRRRSKPSSVLLLNLSFADLCALLT-LPCVLLSASSQN 86

  Fly   135 WPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAVMIWILAILLG 199
            |.....:|.:..|...::.||.:|:|.|||..||..:....|...|......|..:||:::|.:.
Zfish    87 WQLGGGVCVLLSFMTSLTAGVDIFSLAALSVLRYRIVAPSTRPPATPAQVAGTVAVIWLVSIAMA 151

  Fly   200 MPSVLFSDIKSYPVFTATGNMTIEVCSPFRDPEYAKFMVAGKALVYYLLPLSIIGALYIMMAKRL 264
            :|.|.:...        .|..|..|    ....:..|:|.. .||||:.||..|.....::...|
Zfish   152 LPKVTYIQF--------DGGCTWSV----GRGHWLGFLVPA-FLVYYVAPLLCIALHCGLIITHL 203

  Fly   265 HMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHFYPT--------- 320
            :.....:..:.::.::          ..:::...:||.|.:.||:|.|......|:
Zfish   204 YRCRGTLAADHRNKKA----------TALLIGSTLVFAISWLPYYVLEFVNVLSPSLNSASPGPD 258

  Fly   321 -------AEEDFDEFWNVLRIVGFCTSFLNSCVNPVALYCVSG---------VFRQHFN--RYLC 367
                   :..:....|.|..:.......|..|.||...:.:|.         :..||:.  ..|.
Zfish   259 PTAPSSASSTEVSLLWEVTSLSAILLICLAPCWNPPLYFLLSKPALRQLRGLLMHQHWRAATLLQ 323

  Fly   368 CICVKRQP----------HLRQH 380
            .|..|..|          ||.||
Zfish   324 HIVPKHAPTQPHSQAGSQHLPQH 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	64/316 (20%)
		TM helix 1	71..97	CDD:320593	5/25 (20%)
		TM helix 2	104..130	CDD:320593	8/26 (31%)
		TM helix 3	142..172	CDD:320593	11/29 (38%)
		TM helix 4	182..202	CDD:320593	4/19 (21%)
		TM helix 5	234..259	CDD:320593	9/24 (38%)
		TM helix 6	285..315	CDD:320593	7/29 (24%)
		TM helix 7	330..355	CDD:320593	5/24 (21%)
si:ch211-119o8.4	XP_001920980.2	7tm_classA_rhodopsin-like	26..300	CDD:320086	62/297 (21%)
		TM helix 1	26..49	CDD:320086	5/22 (23%)
		TM helix 2	57..82	CDD:320086	7/25 (28%)
		TM helix 3	94..124	CDD:320086	11/29 (38%)
		TM helix 4	135..153	CDD:320086	4/17 (24%)
		TM helix 5	173..198	CDD:320086	9/25 (36%)
		TM helix 6	214..244	CDD:320086	7/39 (18%)
		TM helix 7	255..300	CDD:320086	6/44 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45695
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100