DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCHa2-R and TACR3

DIOPT Version :9

Sequence 1:NP_001356958.1 Gene:CCHa2-R / 35535 FlyBaseID:FBgn0033058 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_001050.1 Gene:TACR3 / 6870 HGNCID:11528 Length:465 Species:Homo sapiens


Alignment Length:373 Identity:97/373 - (26%)
Similarity:166/373 - (44%) Gaps:30/373 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 LAARLADSDGNGANDSG---LLATGQGLEQEQEGLALDMGHNASADGGIVPYVPVLD---RPETY 70
            |.|.||.....||.::|   ||.....|......|.|.:...|.:.    |:..:.:   :|...
Human    24 LTASLAAGAATGAVETGWLQLLDQAGNLSSSPSALGLPVASPAPSQ----PWANLTNQFVQPSWR 84

  Fly    71 IV--TVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQE 133
            |.  ::.|.::..|.||||..::.|...|:.||.:.|.::::||.:|..:......|..|.....
Human    85 IALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHS 149

  Fly   134 SWPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAVMIWILAILL 198
            .|.|..|.||...||...::..|::::||::.:||.||::||:...:...|......|||||.||
Human   150 EWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLL 214

  Fly   199 GMPSVLFSDIKSYPVFTATGNMTIEVCSPFRDPEYAKFMVAGKALVYYLLPLSIIGALYIMMAKR 263
            ..|..|:|..|..|     |.....|..|....::..:.:....|| |..||.|:|..|.::.  
Human   215 AFPQCLYSKTKVMP-----GRTLCFVQWPEGPKQHFTYHIIVIILV-YCFPLLIMGITYTIVG-- 271

  Fly   264 LHMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHFYPTAEEDFDEF 328
            :.:....:||:... :...|.:|:..|.:|::..|:.|.||:.|||::.:....|.....     
Human   272 ITLWGGEIPGDTCD-KYHEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNR----- 330

  Fly   329 WNVLR---IVGFCTSFLNSCVNPVALYCVSGVFRQHFNR-YLCCICVK 372
            |..::   :..|..:..::..||:...|::..||..|.| :..|..:|
Human   331 WKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIK 378

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCHa2-RNP_001356958.1 7tmA_Bombesin_R-like 70..362 CDD:320593 78/296 (26%)
TM helix 1 71..97 CDD:320593 8/27 (30%)
TM helix 2 104..130 CDD:320593 6/25 (24%)
TM helix 3 142..172 CDD:320593 10/29 (34%)
TM helix 4 182..202 CDD:320593 8/19 (42%)
TM helix 5 234..259 CDD:320593 8/24 (33%)
TM helix 6 285..315 CDD:320593 10/29 (34%)
TM helix 7 330..355 CDD:320593 4/27 (15%)
TACR3NP_001050.1 7tmA_NKR_NK3R 86..367 CDD:320669 77/294 (26%)
TM helix 1 87..113 CDD:320669 7/25 (28%)
TM helix 2 120..146 CDD:320669 6/25 (24%)
TM helix 3 158..188 CDD:320669 10/29 (34%)
TM helix 4 199..220 CDD:320669 9/20 (45%)
TM helix 5 244..273 CDD:320669 8/31 (26%)
TM helix 6 292..322 CDD:320669 10/29 (34%)
TM helix 7 335..360 CDD:320669 4/24 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 415..465
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4219
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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