DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCHa2-R and TACR1

DIOPT Version :9

Sequence 1:NP_001356958.1 Gene:CCHa2-R / 35535 FlyBaseID:FBgn0033058 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_001049.1 Gene:TACR1 / 6869 HGNCID:11526 Length:407 Species:Homo sapiens


Alignment Length:351 Identity:89/351 - (25%)
Similarity:156/351 - (44%) Gaps:28/351 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    66 RPETYIV--TVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATI 128
            :|...||  ...||:|.:..|:||..::.|...|:.||.:.|.::::||.|:..:......|...
Human    27 QPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFT 91

  Fly   129 VYTQESWPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAVMIWI 193
            ......|.:....|:...||...::..|::::||::.:||.||::||:...:...|.....:||:
Human    92 YAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWV 156

  Fly   194 LAILLGMPSVLFSDIKSYPVFTATGNMTIEVCSPFRDPE-----YAKFMVAGKALVYYLLPLSII 253
            ||:||..|...:|         .|..|...|......||     |.|.......::.|.|||.:|
Human   157 LALLLAFPQGYYS---------TTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVI 212

  Fly   254 GALYIMMAKRLHMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHFY 318
            |..|.::.  :.:.|..:||: .|.:...|..|:..|.:|::..|..|.||:.|:|:|.|..:..
Human   213 GYAYTVVG--ITLWASEIPGD-SSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274

  Fly   319 PTAEEDFDEFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHF-NRYLCCICVKRQPH--LRQH 380
            |  :....:|...:.:.....:..::..||:...|::..||..| :.:.||..:....:  |...
Human   275 P--DLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMK 337

  Fly   381 ST----ATGMMDNTSVMSMRRSTYVG 402
            ||    ..|.:...|.:....||.||
Human   338 STRYLQTQGSVYKVSRLETTISTVVG 363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCHa2-RNP_001356958.1 7tmA_Bombesin_R-like 70..362 CDD:320593 76/298 (26%)
TM helix 1 71..97 CDD:320593 9/27 (33%)
TM helix 2 104..130 CDD:320593 5/25 (20%)
TM helix 3 142..172 CDD:320593 9/29 (31%)
TM helix 4 182..202 CDD:320593 7/19 (37%)
TM helix 5 234..259 CDD:320593 8/24 (33%)
TM helix 6 285..315 CDD:320593 11/29 (38%)
TM helix 7 330..355 CDD:320593 3/24 (13%)
TACR1NP_001049.1 7tmA_NK1R 33..316 CDD:320668 75/296 (25%)
TM helix 1 35..59 CDD:320668 7/23 (30%)
TM helix 2 68..90 CDD:320668 5/21 (24%)
TM helix 3 106..128 CDD:320668 5/21 (24%)
TM helix 4 149..165 CDD:320668 6/15 (40%)
TM helix 5 194..217 CDD:320668 7/22 (32%)
TM helix 6 247..269 CDD:320668 8/21 (38%)
TM helix 7 284..309 CDD:320668 3/24 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 364..407 89/351 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4219
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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