Protein Alignment CCHa2-R and Npffr1

DIOPT Version :10

• Sequence 1: NP_001356958.1
• Gene: CCHa2-R / 35535
• FlyBaseID: FBgn0033058
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_006256547.1
• Gene: Npffr1 / 64107
• RGDID: 621570
• Length: 468
• Species: Rattus norvegicus
• Alignment Length: 430
• Identity: 110/430 - (25%)
• Similarity: 185/430 - (43%)
• Gaps: 89/430 - (20%)

  Fly    67 PETYIVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYT 131
            |...:....|.|||::.::||..:..|..::|.||.:.|.:||:||::||||.:.|:|...:...
  Rat    77 PVAAMFIAAYVLIFLLCMVGNTLVCFIVLKNRHMRTVTNMFILNLAVSDLLVGIFCMPTTLVDNL 141

  Fly   132 QESWPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAVMIWILAI 196
            ...|||:...|::|...:.:|:..|||||.|::.||:..||:|.|:..|....:||..:||.||:
  Rat   142 ITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALFTIAVIWALAL 206

  Fly   197 LLGMPSVLFSDI-------------KSYPVFTATGNMTIEVCSPFRDPEYAKFMVAGKALVY--- 245
            |:..||.:...:             :|||:::.                :..:...|...||
  Rat   207 LIMCPSAVTLTVTREEHHFMLDARNRSYPLYSC----------------WEAWPEKGMRKVYTAV 255

  Fly   246 -----YLLPLSIIGALYIMMAKRLHMSARNMPG-----EQQSMQSRTQARARLHVARMVVAFVVV 300
                 ||:||::|..:|:.:|::|..:    ||     |:...:....:|.|..|..|:|...:.
  Rat   256 LFAHIYLVPLALIVVMYVRIARKLCQA----PGPARDTEEAVAEGGRTSRRRARVVHMLVMVALF 316

  Fly   301 FFICFFPYHVFELWYHFYPTAEEDFDEFWNVLRIVGF----CTSFLNSCVNPVALYCVSGVFRQH 361
            |.:.:.|..|..|...:...:|...    ::|.:..|    ..:|.:|..||:    :.|.|.::
  Rat   317 FTLSWLPLWVLLLLIDYGELSELQL----HLLSVYAFPLAHWLAFFHSSANPI----IYGYFNEN 373

  Fly   362 FNR-----YLCCICVKRQPHLRQHSTATGMMDNTSVMSMRRSTYVGGTAGNLRASLHRNSNHGVG 421
            |.|     :...:|   .|....|..|.....|   ..:||...|.          .:.|:.|:.
  Rat   374 FRRGFQAAFRAQLC---WPPWAAHKQAYSERPN---RLLRRRVVVD----------VQPSDSGLP 422

  Fly   422 GAGGGVGGGVGSGRVGSFHRQDSMPLQHGN-AHGGGAGGG 460
            ...|...|..|.||         :||::|. ||..|.|.|
  Rat   423 SESGPSSGVPGPGR---------LPLRNGRVAHQDGPGEG 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	84/321 (26%)
		TM helix 1	71..97	CDD:320593	7/25 (28%)
		TM helix 2	104..130	CDD:320593	11/25 (44%)
		TM helix 3	142..172	CDD:320593	11/29 (38%)
		TM helix 4	182..202	CDD:320593	7/19 (37%)
		TM helix 5	234..259	CDD:320593	9/32 (28%)
		TM helix 6	285..315	CDD:320593	9/29 (31%)
		TM helix 7	330..355	CDD:320593	6/28 (21%)
Npffr1	XP_006256547.1	7tmA_NPFFR1	80..378	CDD:320647	86/325 (26%)
		TM helix 1	81..107	CDD:320647	7/25 (28%)
		TM helix 2	114..140	CDD:320647	11/25 (44%)
		TM helix 3	152..182	CDD:320647	11/29 (38%)
		TM helix 4	193..214	CDD:320647	9/20 (45%)
		TM helix 5	249..278	CDD:320647	9/28 (32%)
		TM helix 6	301..331	CDD:320647	9/29 (31%)
		TM helix 7	346..371	CDD:320647	6/28 (21%)