Protein Alignment CCHa2-R and npffr1l2

DIOPT Version :10

• Sequence 1: NP_001356958.1
• Gene: CCHa2-R / 35535
• FlyBaseID: FBgn0033058
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001165168.1
• Gene: npffr1l2 / 570189
• ZFINID: ZDB-GENE-060526-110
• Length: 484
• Species: Danio rerio
• Alignment Length: 475
• Identity: 117/475 - (24%)
• Similarity: 197/475 - (41%)
• Gaps: 99/475 - (20%)

  Fly    36 LEQEQEGLALDMG--------HNASA-DGGIVPYVPVLDR--PETYIVTVLYTLIFIVGVLGNGT 89
            :|..||...|||.        :|::| :...:.|.|....  |....:|:.|..||::.::|||.
Zfish     8 METSQELTTLDMNISLSNAYTNNSNATNHSSITYYPYYQHSLPVAAALTLAYLFIFLLCMVGNGL 72

  Fly    90 LVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESWPFERNMCRISEFFKDISIG 154
            :.:|...:|.||.:.|.:||:||::||||.:.|:|...:......|||...:|::|...:.:|:.
Zfish    73 VCLIVLENRRMRTVTNLFILNLAVSDLLVGVFCIPTTLVDNLITGWPFTNTVCKMSGLVQGMSVS 137

  Fly   155 VSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAVMIWILAILLGMPSVLFSDIK---------- 209
            .|||||.|::.:|:..||.|.:...|..:...|.||||:||:::..||.:...::
Zfish   138 ASVFTLVAIAVDRFRCIVYPFQPKLTLLVAKVTIVMIWVLAVVIMCPSAVTLTVERVEHHYMVRG 202

  Fly   210 -----SYPVFTATGNMTIEVCSPFRDPEYAKFMVAGKALVYYLLPLSIIGALYIMMAKRL----- 264
                 :||:|:...|        :.:|:..|..........||:||::|..:|..:..:|
Zfish   203 EDYNHTYPLFSCFEN--------WANPQMRKVYTTVLFAHIYLIPLTLITLMYGRIGIKLYTTSV 259

  Fly   265 ------------HMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHF 317
                        |.|.:...|:|:.....:|  .::.|.:|:....::|.|.:.|.....|...:
Zfish   260 ISGNDQHDGGQPHTSPQAPGGQQEGRPLISQ--KKIKVIKMLSIVALLFTISWLPLWTLMLLTDY 322

  Fly   318 YPTAEEDFDEFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRYLCCICVKRQPHLRQHST 382
            ....|::.:.....:.......:|.||.|||:    :.|.:.::|.|....:|       |.||.
Zfish   323 GGLNEDELELLSGYVFPFAHWLAFSNSSVNPI----IYGYYNENFKRGFQAVC-------RAHSC 376

  Fly   383 A-TGMMDNTSVMSMRRS----------------------TYVGGTAGNLRASL---HRNS----N 417
            . .||   |:...|||.                      .|..|...|....|   ||.:    |
Zfish   377 CFEGM---TARRGMRRKARGETRDPAVNSNPLNFGARNRVYTDGDLKNSGTCLELEHRRTGRLCN 438

  Fly   418 HGVGGAGGGVGGGVGSGRVG 437
            :.|  .....|..||||..|
Zfish   439 NSV--CSNETGSSVGSGIKG 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	80/323 (25%)
		TM helix 1	71..97	CDD:320593	8/25 (32%)
		TM helix 2	104..130	CDD:320593	11/25 (44%)
		TM helix 3	142..172	CDD:320593	10/29 (34%)
		TM helix 4	182..202	CDD:320593	7/19 (37%)
		TM helix 5	234..259	CDD:320593	7/24 (29%)
		TM helix 6	285..315	CDD:320593	6/29 (21%)
		TM helix 7	330..355	CDD:320593	6/24 (25%)
npffr1l2	NP_001165168.1	7tmA_NPFFR1	53..367	CDD:320647	82/327 (25%)
		TM helix 1	54..80	CDD:320647	8/25 (32%)
		TM helix 2	87..113	CDD:320647	11/25 (44%)
		TM helix 3	125..155	CDD:320647	10/29 (34%)
		TM helix 4	166..187	CDD:320647	9/20 (45%)
		TM helix 5	224..253	CDD:320647	7/28 (25%)
		TM helix 6	290..320	CDD:320647	7/31 (23%)
		TM helix 7	335..360	CDD:320647	7/28 (25%)