Protein Alignment CCHa2-R and grpr

DIOPT Version :10

• Sequence 1: NP_001356958.1
• Gene: CCHa2-R / 35535
• FlyBaseID: FBgn0033058
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_695673.2
• Gene: grpr / 567289
• ZFINID: ZDB-GENE-081015-4
• Length: 376
• Species: Danio rerio
• Alignment Length: 384
• Identity: 133/384 - (34%)
• Similarity: 201/384 - (52%)
• Gaps: 43/384 - (11%)

  Fly    53 ADGGIVPYVPVL-DRPET---------------YIVTVLYTLIFIVGVLGNGTLVIIFFRHRSMR 101
            :|..:.|.|..| |.||.               .|:..:|.|:...|::||.||:..|...:|||
Zfish     2 SDATLTPVVKFLGDSPERSNTSAVPEHPHLHSGIIIATVYALLITAGLIGNVTLIRTFCIVKSMR 66

  Fly   102 NIPNTYILSLALADLLVILVCVPVATIVYTQESWPFERNMCRISEFFKDISIGVSVFTLTALSGE 166
            |:||.::.||||.|:|:::.|.||....:..:.|.|.|..|::..|.:..|:||||||||||:.:
Zfish    67 NVPNLFMSSLALGDVLLLVTCAPVDASKFLADEWLFGRMGCKLIPFIQLTSVGVSVFTLTALAAD 131

  Fly   167 RYCAIVNPLRKLQTKPLTV---FTAVMIWILAILLGMPSVLFSDIKSYPVFTATGNMTIEVCSPF 228
            ||.|||.|: .:|:...::   ..|..||:|:::|.:|..:|||:.::.:  ...|.|.:.|:|:
Zfish   132 RYKAIVKPM-DIQSSKASLKVCLRAASIWMLSMVLAIPEAVFSDLHTFHI--PQTNETFKTCAPY 193

  Fly   229 RDPE----YAKFMVAGKALVYYLLPLSIIGALYIMMAKRLHMSARNMPGEQQSMQSRTQARARLH 289
              |.    :.|.......|:.|::||.||...||.:|:.|..||.|||.|..: ..|.|..:|:.
Zfish   194 --PHAGDLHPKIHSMASFLILYIIPLFIISVYYIFIARSLIQSANNMPVEGNT-HIRRQVESRMR 255

  Fly   290 VARMVVAFVVVFFICFFPYHVFELW--YHFYPTAEEDFDEFWNVLRIVGFCT---SFLNSCVNPV 349
            :|:.|:.||.:|.||:.|.||..|:  || |...:.....|     |...|.   :|.||||||.
Zfish   256 LAKTVLVFVGLFAICWLPNHVIYLYRSYH-YTEVDTSMAHF-----IASVCARILAFTNSCVNPF 314

  Fly   350 ALYCVSGVFRQHFNRYLCCICVK---RQPHLRQHSTATGMMDNTSVMSMRRSTYVGGTA 405
            |||.:|..||:.||:.|||.|..   |....|:|:|....:.:|...|:...:.|.|.|
Zfish   315 ALYLLSKSFRKQFNKQLCCCCPSISLRSQSSRRHNTRLSSLKSTQNHSVASFSLVNGNA 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	111/303 (37%)
		TM helix 1	71..97	CDD:320593	9/25 (36%)
		TM helix 2	104..130	CDD:320593	11/25 (44%)
		TM helix 3	142..172	CDD:320593	16/29 (55%)
		TM helix 4	182..202	CDD:320593	5/22 (23%)
		TM helix 5	234..259	CDD:320593	8/24 (33%)
		TM helix 6	285..315	CDD:320593	12/31 (39%)
		TM helix 7	330..355	CDD:320593	12/27 (44%)
grpr	XP_695673.2	7tm_GPCRs	37..327	CDD:475119	110/301 (37%)
		TM helix 1	37..61	CDD:410628	8/23 (35%)
		TM helix 2	70..92	CDD:410628	10/21 (48%)
		TM helix 3	108..130	CDD:410628	12/21 (57%)
		TM helix 4	153..169	CDD:410628	5/15 (33%)
		TM helix 5	202..225	CDD:410628	7/22 (32%)
		TM helix 6	257..279	CDD:410628	10/21 (48%)
		TM helix 7	295..320	CDD:410628	13/29 (45%)