DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCHa2-R and Rh2

DIOPT Version :9

Sequence 1:	NP_001356958.1	Gene:	CCHa2-R / 35535	FlyBaseID:	FBgn0033058	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_524398.1	Gene:	Rh2 / 42261	FlyBaseID:	FBgn0003248	Length:	381	Species:	Drosophila melanogaster

Alignment Length:	385	Identity:	89/385 - (23%)
Similarity:	160/385 - (41%)	Gaps:	81/385 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 ADSDGNGANDSGLLATGQGLEQEQEGLALDMGHNASAD-GGIVPYVPVLDRPETYIVTVLYTL-I 79
            |.|.|||:....:|.              ||.|..:.. ....|..|::.:     :..|:|| |
  Fly    22 AQSSGNGSVLDNVLP--------------DMAHLVNPYWSRFAPMDPMMSK-----ILGLFTLAI 67

  Fly    80 FIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESWPFERNMCRI 144
            .|:...|||.:|.||...:|:|...|..:|:||.:|..::....||..|.:..|:|......|
  Fly    68 MIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWC-- 130

  Fly   145 SEFFKDISIG-------VSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAVM----IWILAIL- 197
                 ||..|       ||::::..::.:||..||   :.:...|:|:.|::|    ||::|:.
  Fly   131 -----DIYAGCGSLFGCVSIWSMCMIAFDRYNVIV---KGINGTPMTIKTSIMKILFIWMMAVFW 187

  Fly   198 LGMPSVLFSDIKSYPVFTATGNMT---IEVCSPFRDPEYAKFMVAGKALVYYLLPLSIIGALY-- 257
            ..||.:      .:..:...||:|   |:..:...:|.  .:::.....||| .||.:|...|
  Fly   188 TVMPLI------GWSAYVPEGNLTACSIDYMTRMWNPR--SYLITYSLFVYY-TPLFLICYSYWF 243

  Fly   258 IMMAKRLHMSARNMPGEQQSMQSRTQAR-----ARLHVARMVVAFVVVFFICFFPYHV---FELW 314
            |:.|...|..|.....::.:::|...:.     |...:|::.:..:.::|:.:.||.|   |.|:
  Fly   244 IIAAVAAHEKAMREQAKKMNVKSLRSSEDCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLF 308

  Fly   315 YHFYPTAEEDFDEFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRYL---CCICV 371
                     ..|....:..|.|...:..::..||:    |.|:....:...|   |.:||
  Fly   309 ---------KIDGLTPLTTIWGATFAKTSAVYNPI----VYGISHPKYRIVLKEKCPMCV 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	74/317 (23%)
		TM helix 1	71..97	CDD:320593	11/26 (42%)
		TM helix 2	104..130	CDD:320593	8/25 (32%)
		TM helix 3	142..172	CDD:320593	8/36 (22%)
		TM helix 4	182..202	CDD:320593	8/24 (33%)
		TM helix 5	234..259	CDD:320593	7/26 (27%)
		TM helix 6	285..315	CDD:320593	8/37 (22%)
		TM helix 7	330..355	CDD:320593	4/24 (17%)
Rh2	NP_524398.1	7tm_4	67..>237	CDD:304433	49/188 (26%)
Rh2	NP_524398.1	7tm_1	74..336	CDD:278431	67/293 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45695
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010