DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCHa2-R and ednrba

DIOPT Version :9

Sequence 1:	NP_001356958.1	Gene:	CCHa2-R / 35535	FlyBaseID:	FBgn0033058	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_571272.1	Gene:	ednrba / 30442	ZFINID:	ZDB-GENE-980526-16	Length:	426	Species:	Danio rerio

Alignment Length:	354	Identity:	100/354 - (28%)
Similarity:	177/354 - (50%)	Gaps:	39/354 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 YIVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQES 134
            ||.||:..|:|:||::||.||:.|.::::.|||.||..|.||||.|||.|::.:|:.......:.
Zfish    84 YINTVVSCLVFVVGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIMIDIPINVYKLLAKD 148

  Fly   135 WPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIV--NPLRKLQTKPLTVFTAVMIWILAIL 197
            |||...:|::..|.:..|:|:::.:|.|||.:|:.|:.  |.::.:.....|....::||:|:|:
Zfish   149 WPFGVGLCKLVPFIQKTSVGITILSLCALSIDRFRAVSSWNRIKGIGVPKWTAIEIILIWVLSII 213

  Fly   198 LGMPSVLFSDIKSYPVFTATGNMTIEVC--SPFRDPEYAKFMVAGK----ALVYYLLPLSIIGAL 256
            |.:|..:..|:    :........:.:|  .|.:..::.:|....|    ...|:.:||:.....
Zfish   214 LAVPEAIAFDM----ITMDYKGEQLRICLLHPKQRIKFMQFYKKAKDWWLFSFYFCMPLTCTAIF 274

  Fly   257 YIMMAKRLHMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHFYPTA 321
            |.:|...:   .|...|.|.::..  ..:.|..||:.|...|:||.:|:.|.|:..:   ...|.
Zfish   275 YTLMTCEM---LRKKNGVQIALSD--HIKQRREVAKTVFCLVLVFALCWLPLHLSRI---LQRTI 331

  Fly   322 EEDFD-------EFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRYLCCICV-------- 371
            .::.|       .|:.||..:|...:.:|||:||:|||.||..|:..|...|||.|:
Zfish   332 YDERDPNRCELLSFFLVLDYIGINMASVNSCINPIALYMVSKRFKSCFRSCLCCWCLPPEILAMD 396

  Fly   372 KRQPHLR----QHSTATGMMDNTSVMSMR 396
            .:|..::    :..:|...|..||::.:|
Zfish   397 DKQSCIKLKVTERGSAITAMSPTSILQIR 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	89/306 (29%)
		TM helix 1	71..97	CDD:320593	12/25 (48%)
		TM helix 2	104..130	CDD:320593	12/25 (48%)
		TM helix 3	142..172	CDD:320593	10/29 (34%)
		TM helix 4	182..202	CDD:320593	6/19 (32%)
		TM helix 5	234..259	CDD:320593	6/28 (21%)
		TM helix 6	285..315	CDD:320593	10/29 (34%)
		TM helix 7	330..355	CDD:320593	11/24 (46%)
ednrba	NP_571272.1	7tm_4	95..>215	CDD:304433	41/119 (34%)
ednrba	NP_571272.1	7tm_1	100..366	CDD:278431	74/277 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910