DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCHa2-R and Nmbr

DIOPT Version :9

Sequence 1:NP_001356958.1 Gene:CCHa2-R / 35535 FlyBaseID:FBgn0033058 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_036931.1 Gene:Nmbr / 25264 RGDID:3181 Length:390 Species:Rattus norvegicus


Alignment Length:344 Identity:128/344 - (37%)
Similarity:193/344 - (56%) Gaps:22/344 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    71 IVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESW 135
            ::..||.:|..||:|||..||.||..:.:||::||.:|.:||..|||::|.||||....|..:.|
  Rat    45 VIPSLYLIIISVGLLGNIMLVKIFLTNSTMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEW 109

  Fly   136 PFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFT---AVMIWILAIL 197
            .|.:..|::....:..|:|||||||||||.:||.|||||: .:||..:.::|   ||.||::::|
  Rat   110 VFGKLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPM-DMQTSGVVLWTSLKAVGIWVVSVL 173

  Fly   198 LGMPSVLFSDIKSYPVFTATGNMTIEVCSPF--RDPEYAKFMVAGKALVYYLLPLSIIGALYIMM 260
            |.:|..:||::..   ..::.|.:...|.|:  .|..:.|.......|||:|:||.||...|..:
  Rat   174 LAVPEAVFSEVAR---IGSSDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISIYYYHI 235

  Fly   261 AKRLHMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHF-YPTAEED 324
            ||.|..||.|:|||... .::.|...|..:|::|:.||..|..|:||.|:..|:..| |...:..
  Rat   236 AKTLIRSAHNLPGEYNE-HTKKQMETRKRLAKIVLVFVGCFVFCWFPNHILYLYRSFNYKEIDPS 299

  Fly   325 FDEFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRYLCCICVKRQPHLRQHSTATGMMDN 389
            ....  ::.:|....||.||||||.|||.:|..||:|||..|||    .|....:.||:. ::.:
  Rat   300 LGHM--IVTLVARVLSFSNSCVNPFALYLLSESFRKHFNSQLCC----GQKSYPERSTSY-LLSS 357

  Fly   390 TSVMSMRRSTYVGGTAGNL 408
            ::|    |.|.:...|.|:
  Rat   358 SAV----RMTSLKSNAKNV 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCHa2-RNP_001356958.1 7tmA_Bombesin_R-like 70..362 CDD:320593 114/296 (39%)
TM helix 1 71..97 CDD:320593 12/25 (48%)
TM helix 2 104..130 CDD:320593 13/25 (52%)
TM helix 3 142..172 CDD:320593 16/29 (55%)
TM helix 4 182..202 CDD:320593 7/22 (32%)
TM helix 5 234..259 CDD:320593 10/24 (42%)
TM helix 6 285..315 CDD:320593 11/29 (38%)
TM helix 7 330..355 CDD:320593 12/24 (50%)
NmbrNP_036931.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20
7tm_GPCRs 44..335 CDD:421689 114/296 (39%)
TM helix 1 45..71 CDD:410628 12/25 (48%)
TM helix 2 78..104 CDD:410628 13/25 (52%)
TM helix 3 116..146 CDD:410628 16/29 (55%)
TM helix 4 158..178 CDD:410628 7/19 (37%)
TM helix 5 209..234 CDD:410628 10/24 (42%)
TM helix 6 259..289 CDD:410628 11/29 (38%)
TM helix 7 303..328 CDD:410628 12/26 (46%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 177 1.000 Domainoid score I3490
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 219 1.000 Inparanoid score I3481
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1153238at2759
OrthoFinder 1 1.000 - - FOG0001846
OrthoInspector 1 1.000 - - mtm9138
orthoMCL 1 0.900 - - OOG6_106543
Panther 1 1.100 - - O PTHR45695
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X1046
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
1110.970

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