DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCHa2-R and Pgr15l

DIOPT Version :9

Sequence 1:	NP_001356958.1	Gene:	CCHa2-R / 35535	FlyBaseID:	FBgn0033058	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001028533.1	Gene:	Pgr15l / 245526	MGIID:	2676330	Length:	456	Species:	Mus musculus

Alignment Length:	302	Identity:	83/302 - (27%)
Similarity:	146/302 - (48%)	Gaps:	47/302 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 IVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESW 135
            ::|..|.:|.::.:.||..:..:|.:|:.::......|.:||::|:|:||:..|.|...:....|
Mouse    74 VLTFAYAVIIVISLFGNSLVCQVFVKHKEIKKSTGLLIFNLAISDILIILLNSPFALARFLSGQW 138

  Fly   136 PFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAVMIWILAILLGM 200
            .|.|.||.:|.|.:..|:.||..||.|::.:|:..|::|::...|....:|...|||.:|:.|.:
Mouse   139 VFGRIMCHVSRFAQYCSLHVSTLTLMAVAMDRHRVILHPMKPRLTHSQCLFVVAMIWSIAVFLAL 203

  Fly   201 PSVLFSDIKSYPVFTATGNM---TIEVCSP-FRDPE--YAKFMVAGKALVYYLLPLSIIGALYIM 259
            |..::.::     ||.. ||   |...|.| |..|.  .:|::..|..::.|:|||.:|...|..
Mouse   204 PHAIYQNL-----FTLV-NMDGDTRSYCLPSFPGPSILVSKYVDLGTFILLYILPLLVIVVTYSH 262

  Fly   260 MAKRLHMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVF------------- 311
            :.|||.:  :|..|:..:.|.....:.|....||::..|:||.:|:||.:.:
Mouse   263 LGKRLWI--QNAIGDASARQLMAHYQKRKKSIRMLILIVLVFAVCWFPLNFYVVLISSAGVENDS 325

  Fly   312 ELWYHFYPTAEEDFDEFWNVLRIVGFCTSFLNSCVNPVALYC 353
            .|:|.|:          |       |..|  ::|.||. :||
Mouse   326 VLFYAFH----------W-------FAMS--STCYNPF-IYC 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	83/302 (27%)
		TM helix 1	71..97	CDD:320593	6/25 (24%)
		TM helix 2	104..130	CDD:320593	9/25 (36%)
		TM helix 3	142..172	CDD:320593	10/29 (34%)
		TM helix 4	182..202	CDD:320593	6/19 (32%)
		TM helix 5	234..259	CDD:320593	8/24 (33%)
		TM helix 6	285..315	CDD:320593	10/42 (24%)
		TM helix 7	330..355	CDD:320593	7/24 (29%)
Pgr15l	NP_001028533.1	7tm_4	83..360	CDD:304433	80/293 (27%)
Pgr15l	NP_001028533.1	7tm_1	89..346	CDD:278431	78/284 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910