DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCHa2-R and NTSR2

DIOPT Version :9

Sequence 1:NP_001356958.1 Gene:CCHa2-R / 35535 FlyBaseID:FBgn0033058 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_036476.2 Gene:NTSR2 / 23620 HGNCID:8040 Length:410 Species:Homo sapiens


Alignment Length:375 Identity:94/375 - (25%)
Similarity:150/375 - (40%) Gaps:62/375 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    71 IVTVLYTLIFIVGVLGNGTLVIIFFRHRS-----MRNIPNTYILSLALADLLVILVCVPVA--TI 128
            :.|.||.||:.:|..||.....:..:.|:     :|:    ::||||||.||::||.|||.  :.
Human    34 LFTALYALIWALGAAGNALSAHVVLKARAGRAGRLRH----HVLSLALAGLLLLLVGVPVELYSF 94

  Fly   129 VYTQESWPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPL--RKLQTKPLTVFTAVMI 191
            |:....|.|....||...|..::....:|.::..||.||..|:..||  |.|.|...|.:...:.
Human    95 VWFHYPWVFGDLGCRGYYFVHELCAYATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALS 159

  Fly   192 WILAILLGMPSVLFSDIKSYPVFTATG--NMTIEVCSPFRDPEYAKFMVAGKALVYYLLPLSIIG 254
            |..::.|.:|..:....| :.:.||.|  .....||:........:..:....||.::|||::..
Human   160 WAASLGLALPMAVIMGQK-HELETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTA 223

  Fly   255 ALYIMMAKRLHMSARNMP---------------------------------GEQQSMQSRTQARA 286
            .|..:....|......:|                                 |.|.|:......|.
Human   224 FLNGVTVSHLLALCSQVPSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRR 288

  Fly   287 RLHVARMVV---AFVVVFFICFFPYHVFELWYHFYP--TAEEDFDEFWNVLRIVGFCTSFLNSCV 346
            ...:.|.|.   |.||::.||:.|||...|.|.:.|  ...:....|::...:|.....:::|.|
Human   289 IRSLQRSVQVLRAIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAV 353

  Fly   347 NPVALYCVSGVFRQHFNRYLCCIC-----VKRQPHLRQHSTATGMMDNTS 391
            .|:....||..||:.|...:..:|     :||.|...|..|   :||..|
Human   354 TPLLYNAVSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQSPT---LMDTAS 400

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCHa2-RNP_001356958.1 7tmA_Bombesin_R-like 70..362 CDD:320593 84/339 (25%)
TM helix 1 71..97 CDD:320593 8/25 (32%)
TM helix 2 104..130 CDD:320593 13/27 (48%)
TM helix 3 142..172 CDD:320593 9/29 (31%)
TM helix 4 182..202 CDD:320593 3/19 (16%)
TM helix 5 234..259 CDD:320593 6/24 (25%)
TM helix 6 285..315 CDD:320593 12/32 (38%)
TM helix 7 330..355 CDD:320593 4/24 (17%)
NTSR2NP_036476.2 7tmA_NTSR2 33..369 CDD:320478 84/339 (25%)
TM helix 1 33..60 CDD:320478 8/25 (32%)
TM helix 2 68..94 CDD:320478 14/29 (48%)
TM helix 3 108..138 CDD:320478 9/29 (31%)
TM helix 4 152..170 CDD:320478 3/17 (18%)
TM helix 5 203..232 CDD:320478 6/28 (21%)
TM helix 6 290..320 CDD:320478 11/29 (38%)
TM helix 7 337..362 CDD:320478 4/24 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 381..410 8/23 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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