Protein Alignment CCHa2-R and npr-9

DIOPT Version :10

• Sequence 1: NP_001356958.1
• Gene: CCHa2-R / 35535
• FlyBaseID: FBgn0033058
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001361821.1
• Gene: npr-9 / 191320
• WormBaseID: WBGene00013974
• Length: 431
• Species: Caenorhabditis elegans
• Alignment Length: 412
• Identity: 110/412 - (26%)
• Similarity: 176/412 - (42%)
• Gaps: 77/412 - (18%)

  Fly    71 IVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESW 135
            |:..::.:|.:||::||..:||:.| .|.|||..||.|:.||::||:.:|:|||...:.|...:|
 Worm    31 IIPTIFAVIILVGLVGNALVVIVAF-GRQMRNSTNTLIIGLAISDLMFLLLCVPFTAVDYAAPTW 94

  Fly   136 PFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRK--LQTKPLTVFTAVMIWILAILL 198
            .|....|.:..||:..|...||:|||.::.:||.|:|.|:..  |:|...||.....|:|:.|..
 Worm    95 IFPEWTCSMINFFQHTSAYCSVWTLTLMALDRYLAVVYPVESMTLRTPRNTVIALCFIYIIIIAS 159

  Fly   199 GMPSVLFSDIKSY----------PVFT-ATGNMTIEVCSPFRDPEYAKFMVAGKALVYYLLPLSI 252
            .:|......|..|          .:.| ||...|..:...:    :..|.|.|     |:|||.|
 Worm   160 QIPVGRMHGIYVYDFIMEKRSTCAILTIATAEATPTMARTY----FMTFNVFG-----YVLPLGI 215

  Fly   253 IGALYIMMAKRLHMSARNMPGEQQSMQSRT---------------QARARLHVARMVVAFVVVFF 302
            ...||.:|.::|....|  ||..||:..|.               ...|:..|.|:|:..::.:.
 Worm   216 SVVLYGLMLRKLWDMPR--PGNSQSVGGRNLTNRDSGSSIRRRPEATAAKRKVTRLVLCVLITWA 278

  Fly   303 ICFFPYHV-FELWYHFYP-TAEEDFDEFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRY 365
            :|:.|.:| |.:....|| ...........:::|.....::.|||:||:....:|..||:.|.|.
 Worm   279 LCWLPLNVCFFMSGLAYPEPLVISHGVIMVIVQIASQVLAYTNSCLNPILYALMSQSFREGFIRV 343

  Fly   366 LCCICVK----------RQPHLRQHST---------------------ATGMMDN----TSVMSM 395
            :..:..|          |:..||...|                     ::.:.||    |||..:
 Worm   344 MKMLINKLSRGRFCTNYRRSALRTELTHYNQTPAHPANTVVQVSNGERSSLLKDNSSSATSVQPL 408

  Fly   396 RRSTYVGGTAGNLRASLHRNSN 417
            |.|.....|....|:...|:.|
 Worm   409 RTSIQAKKTKNIGRSKSTRSYN 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	92/320 (29%)
		TM helix 1	71..97	CDD:320593	9/25 (36%)
		TM helix 2	104..130	CDD:320593	11/25 (44%)
		TM helix 3	142..172	CDD:320593	12/29 (41%)
		TM helix 4	182..202	CDD:320593	5/19 (26%)
		TM helix 5	234..259	CDD:320593	10/24 (42%)
		TM helix 6	285..315	CDD:320593	8/30 (27%)
		TM helix 7	330..355	CDD:320593	6/24 (25%)
npr-9	NP_001361821.1	7tmA_AstA_R_insect	30..340	CDD:320224	92/320 (29%)
		TM helix 1	31..57	CDD:320224	9/26 (35%)
		TM helix 2	63..89	CDD:320224	11/25 (44%)
		TM helix 3	101..131	CDD:320224	12/29 (41%)
		TM helix 4	143..163	CDD:320224	5/19 (26%)
		TM helix 5	197..226	CDD:320224	11/37 (30%)
		TM helix 6	261..291	CDD:320224	8/29 (28%)
		TM helix 7	308..333	CDD:320224	6/24 (25%)