DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CCHa2-R and EDNRB

DIOPT Version :9

Sequence 1:NP_001356958.1 Gene:CCHa2-R / 35535 FlyBaseID:FBgn0033058 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_001188326.1 Gene:EDNRB / 1910 HGNCID:3180 Length:532 Species:Homo sapiens


Alignment Length:364 Identity:111/364 - (30%)
Similarity:173/364 - (47%) Gaps:56/364 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 GHNASADGGIVP-YVPVLDR-----PET-----------------YIVTVLYTLIFIVGVLGNGT 89
            |.|||....:.| .||..||     |.|                 ||.||:..|:|::|::||.|
Human   147 GSNASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNST 211

  Fly    90 LVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESWPFERNMCRISEFFKDISIG 154
            |:.|.::::.|||.||..|.||||.|||.|::.:|:.......|.|||...||::..|.:..|:|
Human   212 LLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVG 276

  Fly   155 VSVFTLTALSGERYCAIV--NPLRKLQTKPLTVFTAVMIWILAILLGMPSVLFSDI------KSY 211
            ::|.:|.|||.:||.|:.  :.::.:.....|....|:||:::::|.:|..:..||      .||
Human   277 ITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSY 341

  Fly   212 PVFTATGNMTIEVC--SPFRDPEYAKFMVAGK----ALVYYLLPLSIIGALYIMMAKRLHMSARN 270
                      :.:|  .|.:...:.:|....|    ...|:.|||:|....|.:|...:   .|.
Human   342 ----------LRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM---LRK 393

  Fly   271 MPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFEL----WYHFYPTAEEDFDEFWNV 331
            ..|.|.::..  ..:.|..||:.|...|:||.:|:.|.|:..:    .|:.......:...|..|
Human   394 KSGMQIALND--HLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLV 456

  Fly   332 LRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRYLCCIC 370
            |..:|...:.||||:||:|||.||..|:..|...|||.|
Human   457 LDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC 495

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCHa2-RNP_001356958.1 7tmA_Bombesin_R-like 70..362 CDD:320593 95/309 (31%)
TM helix 1 71..97 CDD:320593 11/25 (44%)
TM helix 2 104..130 CDD:320593 12/25 (48%)
TM helix 3 142..172 CDD:320593 12/29 (41%)
TM helix 4 182..202 CDD:320593 5/19 (26%)
TM helix 5 234..259 CDD:320593 8/28 (29%)
TM helix 6 285..315 CDD:320593 10/33 (30%)
TM helix 7 330..355 CDD:320593 12/24 (50%)
EDNRBNP_001188326.1 7tm_4 202..489 CDD:304433 91/301 (30%)
7tm_1 208..474 CDD:278431 81/280 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.