DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCHa2-R and Nmbr

DIOPT Version :9

Sequence 1:NP_001356958.1 Gene:CCHa2-R / 35535 FlyBaseID:FBgn0033058 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_032729.1 Gene:Nmbr / 18101 MGIID:1100525 Length:390 Species:Mus musculus


Alignment Length:304 Identity:122/304 - (40%)
Similarity:175/304 - (57%) Gaps:13/304 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    71 IVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESW 135
            ::..||.:|..||:|||..||.||..:.:|||:||.:|.:||..|||::|.||||....|..:.|
Mouse    45 VIPSLYLIIISVGLLGNIMLVKIFLTNSAMRNVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEW 109

  Fly   136 PFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFT---AVMIWILAIL 197
            .|.:..|::....:..|:|||||||||||.:||.|||||: .:||..:.::|   ||.||::::|
Mouse   110 VFGKLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPM-DMQTSGVLLWTSLKAVGIWVVSVL 173

  Fly   198 LGMPSVLFSDIKSYPVFTATGNMTIEVCSPF--RDPEYAKFMVAGKALVYYLLPLSIIGALYIMM 260
            |.:|..:||::..   ..:..|.:...|.|:  .|..:.|.......|||:|:||.||...|..:
Mouse   174 LAVPEAVFSEVAR---IGSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISIYYYHI 235

  Fly   261 AKRLHMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHF-YPTAEED 324
            ||.|..||.|:|||... .::.|...|..:|::|:.||..|..|:||.||..|:..| |...:..
Mouse   236 AKTLIKSAHNLPGEYNE-HTKKQMETRKRLAKIVLVFVGCFVFCWFPNHVLYLYRSFNYKEIDPS 299

  Fly   325 FDEFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRYLCC 368
            ....  ::.:|....||.||||||.|||.:|..||:|||..|||
Mouse   300 LGHM--IVTLVARVLSFSNSCVNPFALYLLSESFRKHFNSQLCC 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCHa2-RNP_001356958.1 7tmA_Bombesin_R-like 70..362 CDD:320593 116/296 (39%)
TM helix 1 71..97 CDD:320593 12/25 (48%)
TM helix 2 104..130 CDD:320593 13/25 (52%)
TM helix 3 142..172 CDD:320593 16/29 (55%)
TM helix 4 182..202 CDD:320593 7/22 (32%)
TM helix 5 234..259 CDD:320593 10/24 (42%)
TM helix 6 285..315 CDD:320593 12/29 (41%)
TM helix 7 330..355 CDD:320593 12/24 (50%)
NmbrNP_032729.1 7tm_1 60..322 CDD:278431 103/268 (38%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 178 1.000 Domainoid score I3534
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 225 1.000 Inparanoid score I3485
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001846
OrthoInspector 1 1.000 - - mtm8893
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45695
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4897
SonicParanoid 1 1.000 - - X1046
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1010.050

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