Protein Alignment CCHa2-R and tkr-3

DIOPT Version :10

• Sequence 1: NP_001356958.1
• Gene: CCHa2-R / 35535
• FlyBaseID: FBgn0033058
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001343603.1
• Gene: tkr-3 / 177285
• WormBaseID: WBGene00006428
• Length: 400
• Species: Caenorhabditis elegans
• Alignment Length: 388
• Identity: 102/388 - (26%)
• Similarity: 166/388 - (42%)
• Gaps: 65/388 - (16%)

  Fly    24 ANDSGLLAT------GQGLEQEQEGLALDMGHNASADGGIVPYVPVLDRPETYIVTVLYTLIFIV 82
            |.||.|.:|      |.|:..|.....|      |.|.......||    |..|..:||.:|..:
 Worm     5 ATDSILASTITTVIGGAGVLAEAGEAEL------SGDDDFYELTPV----ELIIWCMLYAIIAFM 59

  Fly    83 GVLGN-GTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESWPFERNMCRISE 146
            .|:|| ..|.|..||.| :|:|...:||:|..|||...:..:|........:.|...|::|||..
 Worm    60 AVVGNLLVLYITLFRLR-VRSITTYFILNLGFADLFTGIFAIPFKFQAALFQEWFLPRSLCRIVP 123

  Fly   147 FFKDISIGVSVFTLTALSGERYCAIVNPLRKL------QTKPLTVFTAV-MIWILAILLGMPSVL 204
            :.:.:::.||||||..       :.|:..|.:      |..|.:....| :|||:|:|:.:|..|
 Worm   124 YVETVALTVSVFTLVT-------SAVHEFRTMFFSKCSQMSPRSAKRCVLLIWIMAVLVSLPHGL 181

  Fly   205 FSDIKSYPVFTATGNMTIEVCSP-FRDPEYAKFMVAGKALVYYLLPLSIIGALYIMMA------- 261
            |.:...:|   ...|.:|..|.| :.|..:.|.......::.|.:|:.|:...|.|:|
 Worm   182 FHNTYEFP---DDNNTSIVQCLPVYPDAGWWKTYNVYLVIIQYFVPMIILDTAYTMIAVKIWSLS 243

  Fly   262 -KRLHMSARNMPGEQQSMQSRTQARARL-HVARMVVAFVVVFFICFFPYHVFELWYHFYPTAEED 324
             .|:.:....|..::.|:.|......:| .:.|.::..|..|.:|:||...:.|.....|....
 Worm   244 QSRVELDETKMATQKISVVSMVSPNTQLSQLMRTLIIVVACFSLCWFPLETYLLLNELKPEING- 307

  Fly   325 FDEFWNVLRIVGFCTSFL---NSCVNPVALYCVSGVFRQHFN-------RYLCCICVKRQPHL 377
                |..:.:|.|.:.:|   |||:||:    :.|::...:|       |.:.||. :||..|
 Worm   308 ----WKYINLVFFFSHWLAMSNSCLNPI----IYGLYNTKYNEEYRRLFRQIGCIW-QRQKSL 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	81/312 (26%)
		TM helix 1	71..97	CDD:320593	10/26 (38%)
		TM helix 2	104..130	CDD:320593	7/25 (28%)
		TM helix 3	142..172	CDD:320593	9/29 (31%)
		TM helix 4	182..202	CDD:320593	7/20 (35%)
		TM helix 5	234..259	CDD:320593	5/24 (21%)
		TM helix 6	285..315	CDD:320593	8/30 (27%)
		TM helix 7	330..355	CDD:320593	8/27 (30%)
tkr-3	NP_001343603.1	7tm_GPCRs	47..344	CDD:475119	82/316 (26%)
		TM helix 1	49..73	CDD:320515	8/23 (35%)
		TM helix 2	82..104	CDD:320515	7/21 (33%)
		TM helix 3	120..142	CDD:320515	8/28 (29%)
		TM helix 4	163..179	CDD:320515	6/15 (40%)
		TM helix 5	210..233	CDD:320515	4/22 (18%)
		TM helix 6	275..297	CDD:320515	6/21 (29%)
		TM helix 7	312..337	CDD:320515	9/28 (32%)