DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCHa2-R and tkr-3

DIOPT Version :9

Sequence 1:NP_001356958.1 Gene:CCHa2-R / 35535 FlyBaseID:FBgn0033058 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_001343603.1 Gene:tkr-3 / 177285 WormBaseID:WBGene00006428 Length:400 Species:Caenorhabditis elegans


Alignment Length:388 Identity:102/388 - (26%)
Similarity:166/388 - (42%) Gaps:65/388 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 ANDSGLLAT------GQGLEQEQEGLALDMGHNASADGGIVPYVPVLDRPETYIVTVLYTLIFIV 82
            |.||.|.:|      |.|:..|.....|      |.|.......||    |..|..:||.:|..:
 Worm     5 ATDSILASTITTVIGGAGVLAEAGEAEL------SGDDDFYELTPV----ELIIWCMLYAIIAFM 59

  Fly    83 GVLGN-GTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESWPFERNMCRISE 146
            .|:|| ..|.|..||.| :|:|...:||:|..|||...:..:|........:.|...|::|||..
 Worm    60 AVVGNLLVLYITLFRLR-VRSITTYFILNLGFADLFTGIFAIPFKFQAALFQEWFLPRSLCRIVP 123

  Fly   147 FFKDISIGVSVFTLTALSGERYCAIVNPLRKL------QTKPLTVFTAV-MIWILAILLGMPSVL 204
            :.:.:::.||||||..       :.|:..|.:      |..|.:....| :|||:|:|:.:|..|
 Worm   124 YVETVALTVSVFTLVT-------SAVHEFRTMFFSKCSQMSPRSAKRCVLLIWIMAVLVSLPHGL 181

  Fly   205 FSDIKSYPVFTATGNMTIEVCSP-FRDPEYAKFMVAGKALVYYLLPLSIIGALYIMMA------- 261
            |.:...:|   ...|.:|..|.| :.|..:.|.......::.|.:|:.|:...|.|:|       
 Worm   182 FHNTYEFP---DDNNTSIVQCLPVYPDAGWWKTYNVYLVIIQYFVPMIILDTAYTMIAVKIWSLS 243

  Fly   262 -KRLHMSARNMPGEQQSMQSRTQARARL-HVARMVVAFVVVFFICFFPYHVFELWYHFYPTAEED 324
             .|:.:....|..::.|:.|......:| .:.|.::..|..|.:|:||...:.|.....|.... 
 Worm   244 QSRVELDETKMATQKISVVSMVSPNTQLSQLMRTLIIVVACFSLCWFPLETYLLLNELKPEING- 307

  Fly   325 FDEFWNVLRIVGFCTSFL---NSCVNPVALYCVSGVFRQHFN-------RYLCCICVKRQPHL 377
                |..:.:|.|.:.:|   |||:||:    :.|::...:|       |.:.||. :||..|
 Worm   308 ----WKYINLVFFFSHWLAMSNSCLNPI----IYGLYNTKYNEEYRRLFRQIGCIW-QRQKSL 361

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCHa2-RNP_001356958.1 7tmA_Bombesin_R-like 70..362 CDD:320593 81/312 (26%)
TM helix 1 71..97 CDD:320593 10/26 (38%)
TM helix 2 104..130 CDD:320593 7/25 (28%)
TM helix 3 142..172 CDD:320593 9/29 (31%)
TM helix 4 182..202 CDD:320593 7/20 (35%)
TM helix 5 234..259 CDD:320593 5/24 (21%)
TM helix 6 285..315 CDD:320593 8/30 (27%)
TM helix 7 330..355 CDD:320593 8/27 (30%)
tkr-3NP_001343603.1 7tm_GPCRs 47..344 CDD:391938 82/316 (26%)
TM helix 1 48..74 CDD:341315 9/25 (36%)
TM helix 2 81..106 CDD:341315 7/24 (29%)
TM helix 3 119..149 CDD:341315 11/36 (31%)
TM helix 4 160..181 CDD:341315 7/20 (35%)
TM helix 5 209..238 CDD:341315 7/28 (25%)
TM helix 6 254..299 CDD:341315 11/44 (25%)
TM helix 7 312..337 CDD:341315 9/28 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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