Protein Alignment CCHa2-R and npr-34

DIOPT Version :10

• Sequence 1: NP_001356958.1
• Gene: CCHa2-R / 35535
• FlyBaseID: FBgn0033058
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_497057.2
• Gene: npr-34 / 175131
• WormBaseID: WBGene00013187
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 406
• Identity: 83/406 - (20%)
• Similarity: 161/406 - (39%)
• Gaps: 98/406 - (24%)

  Fly    75 LYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESWPFER 139
            ||..:|:||.:||..::.:..|.:.|||:.|.::.||:.|||.:|..|||:..:.|...:|...|
 Worm    78 LYLTVFLVGTIGNSMVIFVVNRFKRMRNVTNIFLASLSTADLCLIWFCVPIMFMKYMSHTWSMGR 142

  Fly   140 NMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAV--------MIWILAI 196
            ..|....:.:..:...||.|:|.:|.||:.||..|:|.:.      |:::        :||:.:.
 Worm   143 FACYSVHYIQQFTCFCSVLTMTMISFERFLAIAYPMRNIW------FSSIGRAKKVILLIWMSSA 201

  Fly   197 LLGMPSVLFSDIKS----------------------YP-----------------VFTATGNMTI 222
            :|.:|:.:..|.::                      ||                 :|..   :|:
 Worm   202 VLAVPTAVRMDYETNLSLSGQRVHWCRRRFPAQFLGYPRTSLNKAYAMYQLLLLIIFPV---LTM 263

  Fly   223 EVCSPFRDPEYAKF-----------MVAGKALV--------------YYLLPLSIIGALYIMMAK 262
            .:|       ||:.           ::..:|:|              |..:|:       |..::
 Worm   264 SIC-------YARVSAIVYKSSKDRVILSQAMVAFSKAATDAVTFSGYSAIPM-------ITTSR 314

  Fly   263 RLHMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHFYPTAEEDFDE 327
            .|..:...:........:|.....:..:.:|:::.|.::.:|:.|..|.||...|.........:
 Worm   315 NLKTANTTIKSYSNHRNNRVAEANKKQIVQMLISIVCMYTVCWLPTIVDELLTSFGYICRTSNTQ 379

  Fly   328 FWNVLRIVGF-CTSFLNSCVNPVALYCVSGVFRQHFNRYLCCICVKRQPHLRQHSTATGMMDNTS 391
            ....:| :|| ..::..||:||:....:|..||..|......: ..|...:.:..:..|...:.|
 Worm   380 TLKHMR-MGFNALTYCQSCINPILYAFISQNFRSTFKTAYSRM-KSRLQGVEEMRSRMGSCSSAS 442

  Fly   392 VMSMRRSTYVGGTAGN 407
            :||.|....:.|::.|
 Worm   443 MMSTRNQHRIYGSSFN 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	74/359 (21%)
		TM helix 1	71..97	CDD:320593	7/21 (33%)
		TM helix 2	104..130	CDD:320593	10/25 (40%)
		TM helix 3	142..172	CDD:320593	9/29 (31%)
		TM helix 4	182..202	CDD:320593	4/27 (15%)
		TM helix 5	234..259	CDD:320593	5/49 (10%)
		TM helix 6	285..315	CDD:320593	7/29 (24%)
		TM helix 7	330..355	CDD:320593	7/25 (28%)
npr-34	NP_497057.2	7tmA_GPRnna14-like	75..414	CDD:320132	74/359 (21%)
		TM helix 1	75..100	CDD:320132	7/21 (33%)
		TM helix 2	107..132	CDD:320132	10/24 (42%)
		TM helix 3	145..175	CDD:320132	9/29 (31%)
		TM helix 4	188..209	CDD:320132	4/20 (20%)
		TM helix 5	244..269	CDD:320132	4/34 (12%)
		TM helix 6	337..367	CDD:320132	7/29 (24%)
		TM helix 7	382..407	CDD:320132	7/25 (28%)