DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CCHa2-R and Ednrb

DIOPT Version :9

Sequence 1:NP_001356958.1 Gene:CCHa2-R / 35535 FlyBaseID:FBgn0033058 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_001129533.1 Gene:Ednrb / 13618 MGIID:102720 Length:442 Species:Mus musculus


Alignment Length:318 Identity:103/318 - (32%)
Similarity:165/318 - (51%) Gaps:31/318 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 YIVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQES 134
            ||.|::..|:|::|::||.||:.|.::::.|||.||..|.||||.|||.|::.:|:.|.....|.
Mouse   102 YINTIVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINTYKLLAED 166

  Fly   135 WPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIV--NPLRKLQTKPLTVFTAVMIWILAIL 197
            |||...||::..|.:..|:|::|.:|.|||.:||.|:.  :.::.:.....|....|:||:::::
Mouse   167 WPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVV 231

  Fly   198 LGMP-----SVLFSDIKSYPVFTATGNMTIEVC--SPFRDPEYAKFMVAGK----ALVYYLLPLS 251
            |.:|     .::.||.|..|         :.||  :||:...:.:|....|    ...|:.|||:
Mouse   232 LAVPEAIGFDMITSDYKGKP---------LRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLA 287

  Fly   252 IIGALYIMMAKRLHMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFE-LWY 315
            |....|.:|...:   .|...|.|.::..  ..:.|..||:.|...|:||.:|:.|.|:.. |..
Mouse   288 ITAVFYTLMTCEM---LRKKSGMQIALND--HLKQRREVAKTVFCLVLVFALCWLPLHLSRILKL 347

  Fly   316 HFYPTAEE---DFDEFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRYLCCIC 370
            ..|..:..   :...|..||..:|...:.||||:||:|||.||..|:..|...|||.|
Mouse   348 TLYDQSNPHRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC 405

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCHa2-RNP_001356958.1 7tmA_Bombesin_R-like 70..362 CDD:320593 98/308 (32%)
TM helix 1 71..97 CDD:320593 10/25 (40%)
TM helix 2 104..130 CDD:320593 13/25 (52%)
TM helix 3 142..172 CDD:320593 12/29 (41%)
TM helix 4 182..202 CDD:320593 6/24 (25%)
TM helix 5 234..259 CDD:320593 8/28 (29%)
TM helix 6 285..315 CDD:320593 11/30 (37%)
TM helix 7 330..355 CDD:320593 12/24 (50%)
EdnrbNP_001129533.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 50..84
7tmA_ET-BR 102..397 CDD:320642 98/308 (32%)
TM helix 1 103..129 CDD:320642 10/25 (40%)
TM helix 2 136..162 CDD:320642 13/25 (52%)
TM helix 3 174..204 CDD:320642 12/29 (41%)
TM helix 4 216..236 CDD:320642 5/19 (26%)
TM helix 5 270..295 CDD:320642 7/24 (29%)
TM helix 6 316..346 CDD:320642 10/29 (34%)
TM helix 7 365..390 CDD:320642 12/24 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.