DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCHa2-R and GPR151

DIOPT Version :9

Sequence 1:NP_001356958.1 Gene:CCHa2-R / 35535 FlyBaseID:FBgn0033058 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_919227.2 Gene:GPR151 / 134391 HGNCID:23624 Length:419 Species:Homo sapiens


Alignment Length:379 Identity:86/379 - (22%)
Similarity:152/379 - (40%) Gaps:65/379 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 LAARLADSDGNGANDSGLLATGQGLEQEQEGLALDMGHNASADGGIVPYVPVLDRPETYIVTVLY 76
            |||..|||:.:..|                   :...|...|.|    |:|...:....|:..|.
Human     2 LAAAFADSNSSSMN-------------------VSFAHLHFAGG----YLPSDSQDWRTIIPALL 43

  Fly    77 TLIFIVGVLGNGTLVIIFFRHRSMRNIP---NTYILSLALADLLVILVCVPVATIVYTQESWPFE 138
            ..:.:||.:|| ..||....|.:.:..|   ::.||:|:||||.::|...|:....|::..|...
Human    44 VAVCLVGFVGN-LCVIGILLHNAWKGKPSMIHSLILNLSLADLSLLLFSAPIRATAYSKSVWDLG 107

  Fly   139 RNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTA-VMIWILAILLGMPS 202
            ..:|:.|::|....:.....|:..::...:....:|.:::.....|:::. |.||.:|.||.:|.
Human   108 WFVCKSSDWFIHTCMAAKSLTIVVVAKVCFMYASDPAKQVSIHNYTIWSVLVAIWTVASLLPLPE 172

  Fly   203 VLFSDIKSYPVFTATGNMTIEVCSPFRDPEYAKFM-VAGK--ALVYYLLPLSIIGALYIMMA--- 261
            ..||.|:.:.        .:|:|.........:|| :.||  .|:.:.||| ...:.|...|   
Human   173 WFFSTIRHHE--------GVEMCLVDVPAVAEEFMSMFGKLYPLLAFGLPL-FFASFYFWRAYDQ 228

  Fly   262 -KRLHMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELW-YHFY---PTA 321
             |:.....:|:         |.|.|:: .|..|:::..::..:.:.|..|..|| :|..   |..
Human   229 CKKRGTKTQNL---------RNQIRSK-QVTVMLLSIAIISALLWLPEWVAWLWVWHLKAAGPAP 283

  Fly   322 EEDFDEFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRYLCCICVKRQP 375
            .:.|.....||       .|..|..||:....:|..||:........:..|:.|
Human   284 PQGFIALSQVL-------MFSISSANPLIFLVMSEEFREGLKGVWKWMITKKPP 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCHa2-RNP_001356958.1 7tmA_Bombesin_R-like 70..362 CDD:320593 72/306 (24%)
TM helix 1 71..97 CDD:320593 8/25 (32%)
TM helix 2 104..130 CDD:320593 10/28 (36%)
TM helix 3 142..172 CDD:320593 4/29 (14%)
TM helix 4 182..202 CDD:320593 7/20 (35%)
TM helix 5 234..259 CDD:320593 9/27 (33%)
TM helix 6 285..315 CDD:320593 7/30 (23%)
TM helix 7 330..355 CDD:320593 6/24 (25%)
GPR151NP_919227.2 7tmA_GPR151 38..317 CDD:320133 72/305 (24%)
TM helix 1 38..64 CDD:320133 8/26 (31%)
TM helix 2 73..98 CDD:320133 9/24 (38%)
TM helix 3 110..140 CDD:320133 4/29 (14%)
TM helix 4 153..174 CDD:320133 8/20 (40%)
TM helix 5 199..228 CDD:320133 9/29 (31%)
TM helix 6 243..273 CDD:320133 6/30 (20%)
TM helix 7 285..310 CDD:320133 7/31 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 330..419 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45695
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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