Protein Alignment CCHa2-R and Cckar

DIOPT Version :10

• Sequence 1: NP_001356958.1
• Gene: CCHa2-R / 35535
• FlyBaseID: FBgn0033058
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_033957.1
• Gene: Cckar / 12425
• MGIID: 99478
• Length: 436
• Species: Mus musculus
• Alignment Length: 430
• Identity: 104/430 - (24%)
• Similarity: 173/430 - (40%)
• Gaps: 111/430 - (25%)

  Fly    64 LDRP------ETYIVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVC 122
            ||:|      ::.:..:||:.||::.||||..::.:..|::.||.:.|.::||||::||::.|.|
Mouse    30 LDQPQPSKEWQSAVQILLYSFIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFC 94

  Fly   123 VPVATIVYTQESWPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPL--RKLQTKPLTV 185
            :|...|....:.:.|...:|:.:.:|...|:.||.|.|.|:|.|||.||..||  |..|||...:
Mouse    95 MPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHAL 159

  Fly   186 FTAVMIWILAILLGMPSVLFSDIKSYPVFTATGNMTIEVC-----SPFRDPEYAKFMVAGKALVY 245
            ......|.|:..:..|..::|::..   ||...|.|..:|     |......:..|::    |:.
Mouse   160 KVIAATWCLSFTIMTPYPIYSNLVP---FTKNNNQTANMCRFLLPSDAMQQSWQTFLL----LIL 217

  Fly   246 YLLPLSIIGALYIMM-----------------AKRLHMSA----------------------RNM 271
            :|:|..::...|.::                 ||...:|:                      ::.
Mouse   218 FLIPGVVMVVAYGLISLELYQGIKFDASQKKSAKEKRLSSGGGGGGGSSSSRYEDSDGCYLQKSR 282

  Fly   272 PGEQQSMQ------------------SRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHFY 318
            |..:..:|                  |.....|:..|.||::..||:||:|:.|......| ..|
Mouse   283 PPRKLELQQLSTSSSGGRINRIRSSGSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAW-RAY 346

  Fly   319 PTAEEDFDEFWNVLRIVGFCTSFLNSCVNPVALYC-VSGVFRQHFNRYLCCICVKRQPHLRQHST 382
            .|...:.......:..: ...|:.:|||||: :|| ::..||..|.....| |....|
Mouse   347 DTVSAEKHLSGTPISFI-LLLSYTSSCVNPI-IYCFMNKRFRLGFMATFPC-CPNPGP------- 401

  Fly   383 ATGMMDNTSVMSMRRSTYVGGTAG------NLRASLHRNS 416
                            |.|.|..|      .:||||.|.|
Mouse   402 ----------------TGVRGEVGEEEDGRTIRASLSRYS 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	87/356 (24%)
		TM helix 1	71..97	CDD:320593	8/25 (32%)
		TM helix 2	104..130	CDD:320593	11/25 (44%)
		TM helix 3	142..172	CDD:320593	13/29 (45%)
		TM helix 4	182..202	CDD:320593	2/19 (11%)
		TM helix 5	234..259	CDD:320593	5/24 (21%)
		TM helix 6	285..315	CDD:320593	10/29 (34%)
		TM helix 7	330..355	CDD:320593	8/25 (32%)
Cckar	NP_033957.1	CholecysA-Rec_N	1..47	CDD:462713	3/16 (19%)
		7tm_GPCRs	42..389	CDD:475119	87/356 (24%)
		TM helix 1	44..68	CDD:410628	8/23 (35%)
		TM helix 2	77..99	CDD:410628	10/21 (48%)
		TM helix 3	115..137	CDD:410628	7/21 (33%)
		TM helix 4	160..176	CDD:410628	2/15 (13%)
		TM helix 5	207..230	CDD:410628	4/26 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..280		1/27 (4%)
		TM helix 6	320..342	CDD:410628	8/21 (38%)
		TM helix 7	357..382	CDD:410628	8/26 (31%)