Protein Alignment CCHa2-R and gpr37

DIOPT Version :10

• Sequence 1: NP_001356958.1
• Gene: CCHa2-R / 35535
• FlyBaseID: FBgn0033058
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_002941877.2
• Gene: gpr37 / 100486656
• XenbaseID: XB-GENE-962315
• Length: 603
• Species: Xenopus tropicalis
• Alignment Length: 347
• Identity: 82/347 - (23%)
• Similarity: 150/347 - (43%)
• Gaps: 38/347 - (10%)

  Fly    59 PYVPVL-DRPETYIVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVC 122
            |:.|:. |....|.|..|..:||::|::||..::.|...:..||:|.|:.:.:||..|.|:|..|
 Frog   240 PFYPLTEDSYGAYAVMCLSVIIFVIGIMGNMAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFC 304

  Fly   123 VPVATIVYTQESWPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNP---LRKLQTKPLT 184
            :|:.......:.|..|...|:|..:.:..|:||:.|||.||..:|:.|..|.   ...::....|
 Frog   305 LPLVIFHELTKKWLLEDFSCKIIPYIEIASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCTST 369

  Fly   185 VFTAVMIWILAILLGMPSVLFSDIKSYPVFTATG--------NMTIEVCSPFRDPEYAKFMVAGK 241
            .....:||:.|::|.:|.|:...:.    ...||        ...:::.:...|..|...:....
 Frog   370 TAKLAVIWVGALVLALPEVVLRQLS----VEDTGVNGRFLRERCVVKISTELPDTIYVLALTYDG 430

  Fly   242 ALV------YYLLPLSIIGALYIMMAKRLHMSARNMP-GEQQSMQSRTQARARLHVARMVVAFVV 299
            |.:      |:.||........::.|:::..:.:... |.::.:|...|...      .|||..:
 Frog   431 ARLWWYFGCYFCLPTLFTITCSLVTARKIKRAEKACTRGNKRQIQLEGQMNC------TVVALTI 489

  Fly   300 VFFICFFPYHVFEL--WYHFYPTAEEDFDEFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHF 362
            ::..|..|.::..:  .|.....:.:..|    :|.::.....|..|||.||.|:|:...|.:.|
 Frog   490 LYGFCVIPENICNIVAAYMSSGVSRQTLD----LLHLISQFLLFFKSCVTPVLLFCLCKPFSRAF 550

  Fly   363 NRYLCCICVKRQPHLRQHSTAT 384
            ....||.|   ...:::.||||
 Frog   551 MECCCCCC---DECIQKSSTAT 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	71/311 (23%)
		TM helix 1	71..97	CDD:320593	8/25 (32%)
		TM helix 2	104..130	CDD:320593	8/25 (32%)
		TM helix 3	142..172	CDD:320593	12/29 (41%)
		TM helix 4	182..202	CDD:320593	5/19 (26%)
		TM helix 5	234..259	CDD:320593	4/30 (13%)
		TM helix 6	285..315	CDD:320593	5/31 (16%)
		TM helix 7	330..355	CDD:320593	9/24 (38%)
gpr37	XP_002941877.2	7tmA_GPR37	252..550	CDD:320255	71/311 (23%)
		TM helix 1	253..279	CDD:320255	8/25 (32%)
		TM helix 2	286..312	CDD:320255	8/25 (32%)
		TM helix 3	324..354	CDD:320255	12/29 (41%)
		TM helix 4	367..387	CDD:320255	5/19 (26%)
		TM helix 5	429..454	CDD:320255	4/24 (17%)
		TM helix 6	475..505	CDD:320255	7/35 (20%)
		TM helix 7	518..543	CDD:320255	10/28 (36%)