Protein Alignment CCHa2-R and tacr3

DIOPT Version :10

• Sequence 1: NP_001356958.1
• Gene: CCHa2-R / 35535
• FlyBaseID: FBgn0033058
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_002934808.1
• Gene: tacr3 / 100486525
• XenbaseID: XB-GENE-985728
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 382
• Identity: 98/382 - (25%)
• Similarity: 172/382 - (45%)
• Gaps: 54/382 - (14%)

  Fly    73 TVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESWPF 137
            ::.|..:..|.|.||..::.|...|:.||.:.|.::::||.:|..:......|..|......|.|
 Frog    53 SLAYGSMVAVAVFGNIIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHNEWYF 117

  Fly   138 ERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAVMIWILAILLGMPS 202
            ....||...||...||..|:::::|::.:||.||::||:...:...|......|||.||||..|.
 Frog   118 GEAYCRFHNFFPITSIFASIYSMSAIAVDRYMAIIDPLKPRLSATSTKVVIGSIWIFAILLAFPQ 182

  Fly   203 VLFSDIKSYPVFTATGNMTIEVCSPFRDPEYA-KFMVAGKALVYYLLPLSIIGALYIMMAKRLHM 266
            .|:|.|:    .|.|..:.:.|. |.:|.... :|::   .|:.|:|||.::|..|.::.  :.:
 Frog   183 CLYSKIR----VTRTRTLCMLVW-PGKDERLTYQFIL---VLLVYVLPLIVMGVTYTIVG--ITL 237

  Fly   267 SARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHFYPTAEEDFDEFWNV 331
            ....:||: .|.:...|.||:..|.:|::..||.|.||:.|||:|     |...|.:...:.|..
 Frog   238 WGGEIPGD-TSDKYHEQLRAKRKVVKMMIVVVVTFAICWLPYHIF-----FLADALDIKLDRWKY 296

  Fly   332 LR---IVGFCTSFLNSCVNPVALYCVSGVFRQHFNR-YLCCICVK-----------------RQP 375
            ::   :..|..:..::..||:...|::..||..|.| :..|..::                 ||.
 Frog   297 IQQIYLAIFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIEVSSYDELELKSTRFHPTRQS 361

  Fly   376 HL----RQHSTATGMMDNTSVMSMR------------RSTYVGGTAGNLRASLHRNS 416
            .|    |..|:.|.:.|...|.:.:            .||:.|.:..|.:::...:|
 Frog   362 SLYTVSRMESSMTVVFDPNDVENNKPSHSHKKRAATSESTFNGCSRRNSKSASTNSS 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	82/292 (28%)
		TM helix 1	71..97	CDD:320593	6/23 (26%)
		TM helix 2	104..130	CDD:320593	6/25 (24%)
		TM helix 3	142..172	CDD:320593	11/29 (38%)
		TM helix 4	182..202	CDD:320593	8/19 (42%)
		TM helix 5	234..259	CDD:320593	8/25 (32%)
		TM helix 6	285..315	CDD:320593	13/29 (45%)
		TM helix 7	330..355	CDD:320593	4/27 (15%)
tacr3	XP_002934808.1	7tm_GPCRs	50..330	CDD:475119	82/292 (28%)
		TM helix 1	52..76	CDD:320669	6/22 (27%)
		TM helix 2	85..107	CDD:320669	5/21 (24%)
		TM helix 3	123..145	CDD:320669	7/21 (33%)
		TM helix 4	166..182	CDD:320669	7/15 (47%)
		TM helix 5	208..231	CDD:320669	7/25 (28%)
		TM helix 6	261..283	CDD:320669	10/26 (38%)
		TM helix 7	298..323	CDD:320669	4/24 (17%)