DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCHa2-R and tacr3

DIOPT Version :9

Sequence 1:	NP_001356958.1	Gene:	CCHa2-R / 35535	FlyBaseID:	FBgn0033058	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	XP_002934808.1	Gene:	tacr3 / 100486525	XenbaseID:	XB-GENE-985728	Length:	431	Species:	Xenopus tropicalis

Alignment Length:	382	Identity:	98/382 - (25%)
Similarity:	172/382 - (45%)	Gaps:	54/382 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 TVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESWPF 137
            ::.|..:..|.|.||..::.|...|:.||.:.|.::::||.:|..:......|..|......|.|
Frog    53 SLAYGSMVAVAVFGNIIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHNEWYF 117

  Fly   138 ERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAVMIWILAILLGMPS 202
            ....||...||...||..|:::::|::.:||.||::||:...:...|......|||.||||..|.
Frog   118 GEAYCRFHNFFPITSIFASIYSMSAIAVDRYMAIIDPLKPRLSATSTKVVIGSIWIFAILLAFPQ 182

  Fly   203 VLFSDIKSYPVFTATGNMTIEVCSPFRDPEYA-KFMVAGKALVYYLLPLSIIGALYIMMAKRLHM 266
            .|:|.|:    .|.|..:.:.|. |.:|.... :|::   .|:.|:|||.::|..|.::.  :.:
Frog   183 CLYSKIR----VTRTRTLCMLVW-PGKDERLTYQFIL---VLLVYVLPLIVMGVTYTIVG--ITL 237

  Fly   267 SARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHFYPTAEEDFDEFWNV 331
            ....:||: .|.:...|.||:..|.:|::..||.|.||:.|||:|     |...|.:...:.|..
Frog   238 WGGEIPGD-TSDKYHEQLRAKRKVVKMMIVVVVTFAICWLPYHIF-----FLADALDIKLDRWKY 296

  Fly   332 LR---IVGFCTSFLNSCVNPVALYCVSGVFRQHFNR-YLCCICVK-----------------RQP 375
            ::   :..|..:..::..||:...|::..||..|.| :..|..::                 ||.
Frog   297 IQQIYLAIFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIEVSSYDELELKSTRFHPTRQS 361

  Fly   376 HL----RQHSTATGMMDNTSVMSMR------------RSTYVGGTAGNLRASLHRNS 416
            .|    |..|:.|.:.|...|.:.:            .||:.|.:..|.:::...:|
Frog   362 SLYTVSRMESSMTVVFDPNDVENNKPSHSHKKRAATSESTFNGCSRRNSKSASTNSS 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	82/292 (28%)
		TM helix 1	71..97	CDD:320593	6/23 (26%)
		TM helix 2	104..130	CDD:320593	6/25 (24%)
		TM helix 3	142..172	CDD:320593	11/29 (38%)
		TM helix 4	182..202	CDD:320593	8/19 (42%)
		TM helix 5	234..259	CDD:320593	8/25 (32%)
		TM helix 6	285..315	CDD:320593	13/29 (45%)
		TM helix 7	330..355	CDD:320593	4/27 (15%)
tacr3	XP_002934808.1	7tm_4	58..>181	CDD:304433	38/122 (31%)
tacr3	XP_002934808.1	7tm_1	66..319	CDD:278431	76/268 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910